Table 5 Case-control analysis of ADAM33 S_2 allele frequencies and genotype distributions (genotypes in comparison with controls).

Homozygotes for wild type

78

(52.0%)

33

(55.0%)

45

(50.0%)

74

(48.7%)

Heterozygotes for mutation

61

(40.7%)

26

(43.3%)

35

(38.9%)

72

(47.4%)

Homozygotes for mutation

11

(7.3%)

1

(1.7%)

10

(11.1%)

6

(4.0%)

Carrier frequency of the mutant allele

27.7%

(83/300)

23.3%

(28/120)

30.6%

(55/180)

27.6%

(84/304)

P-value (Armitage's trend test)

0.99

0.32

0.47