Skip to main content

Table 5 Case-control analysis of ADAM33 S_2 allele frequencies and genotype distributions (genotypes in comparison with controls).

From: ADAM33 gene polymorphisms in chronic obstructive pulmonary disease

  All COPD Stable COPD Unstable COPD Control
Homozygotes for wild type 78
(52.0%)
33
(55.0%)
45
(50.0%)
74
(48.7%)
Heterozygotes for mutation 61
(40.7%)
26
(43.3%)
35
(38.9%)
72
(47.4%)
Homozygotes for mutation 11
(7.3%)
1
(1.7%)
10
(11.1%)
6
(4.0%)
Carrier frequency of the mutant allele 27.7%
(83/300)
23.3%
(28/120)
30.6%
(55/180)
27.6%
(84/304)
P-value (Armitage's trend test) 0.99 0.32 0.47