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Table 1 Base data of patients.

From: Maternal smoking promotes chronic obstructive lung disease in the offspring as adults

Parameter Non-Exacerbaters (NE) > 1 Exacerbation (1E) Statistics/test used
Patient number n = 133 n = 158  
Age (y)* 67 ± 10 67 ± 10 P = 0.615/t-test
Gender (n, women/men) 45/85 50/107 P = 0.678/χ2-test
Age* at beginning of cigarette smoking 19 ± 5 20 ± 6 P = 0.652/t-test
Pack years 36.5 ± 20.6 37.9 ± 24.1 P = 0.371/t-test
Non-smoking since years (before interview) 13.2 ± 12.0 12.2 ± 9.9 P = 0.154/t-test
FEV1 % predicted* 62.7 + 20.9 9 43.1 + 20.9 9 P < 0.001/t-test
FEV1 (l) 1.6 ± 0.7 1.2 ± 0.61 P < 0.001/t-test
FVC (% predicted) 73.4 ± 18.6 59.7 ± 18.1 P < 0.001/t-test
FVC (l) 2.4 ± 0.9 2.2 + 0.7 P < 0.001/t-test
FEV1/FVC (%) 62.5 ± 15.1 56.6 ± 18.0 P < 0.01/t-test
Rt$ (cm H2O/l × sec.) 0.57 ± 0.33 1.19 ± 1.29 P < 0.01/t-test
Reversibility test§
% 8.1 ± 3.5 5.71 ± 4.6 P = 0.452/t-test
Ml 110.5 ± 47.9 129.5 ± 61.3 P = 0.768/t-test
pO2 (mmHg) 66,8 ± 13,0 58,8 ± 16,2 P < 0.01/t-test
pCO2 (mmHg) 37.5 ± 5.8 42.9 ± 12.7 P < 0.01/t-test
Patients (%) reporting chronic bronchitis (WHO definition) 30.4 30.4 P = 1.000/χ2-test
pneumonias or asthma (age* < 18 y) 8.0 13.8 P = 0.165
  13.3 10.9 P = 0.565
Beginning of exercise induced dyspnea (age, y*) 49 ± 16 46 ± 17 P = 0.186/t-test
Reported exacerbations# (n, 2003-1980) 0 3 P < 0.001/U-test
  1. Bronchitis was defined according to the World Health Organization [37].
  2. COPD exacerbation was defined as hospitalization and treatment with systemic corticosteroids or antibiotics [9, 10, 38]. $total resistance (measured with body plethysmography); *mean, #median, §tested with salbutamol (400 μg); y = years.