Table 1 Base data of patients.
From: Maternal smoking promotes chronic obstructive lung disease in the offspring as adults
Parameter | Non-Exacerbaters (NE) | > 1 Exacerbation (1E) | Statistics/test used |
|---|---|---|---|
Patient number | n = 133 | n = 158 | |
Age (y)* | 67 ± 10 | 67 ± 10 | P = 0.615/t-test |
Gender (n, women/men) | 45/85 | 50/107 | P = 0.678/χ2-test |
Age* at beginning of cigarette smoking | 19 ± 5 | 20 ± 6 | P = 0.652/t-test |
Pack years | 36.5 ± 20.6 | 37.9 ± 24.1 | P = 0.371/t-test |
Non-smoking since years (before interview) | 13.2 ± 12.0 | 12.2 ± 9.9 | P = 0.154/t-test |
FEV1 % predicted* | 62.7 + 20.9 | 9 43.1 + 20.9 | 9 P < 0.001/t-test |
FEV1 (l) | 1.6 ± 0.7 | 1.2 ± 0.61 | P < 0.001/t-test |
FVC (% predicted) | 73.4 ± 18.6 | 59.7 ± 18.1 | P < 0.001/t-test |
FVC (l) | 2.4 ± 0.9 | 2.2 + 0.7 | P < 0.001/t-test |
FEV1/FVC (%) | 62.5 ± 15.1 | 56.6 ± 18.0 | P < 0.01/t-test |
Rt$ (cm H2O/l × sec.) | 0.57 ± 0.33 | 1.19 ± 1.29 | P < 0.01/t-test |
Reversibility test§ | |||
% | 8.1 ± 3.5 | 5.71 ± 4.6 | P = 0.452/t-test |
Ml | 110.5 ± 47.9 | 129.5 ± 61.3 | P = 0.768/t-test |
pO2 (mmHg) | 66,8 ± 13,0 | 58,8 ± 16,2 | P < 0.01/t-test |
pCO2 (mmHg) | 37.5 ± 5.8 | 42.9 ± 12.7 | P < 0.01/t-test |
Patients (%) reporting chronic bronchitis (WHO definition) | 30.4 | 30.4 | P = 1.000/χ2-test |
pneumonias or asthma (age* < 18 y) | 8.0 | 13.8 | P = 0.165 |
13.3 | 10.9 | P = 0.565 | |
Beginning of exercise induced dyspnea (age, y*) | 49 ± 16 | 46 ± 17 | P = 0.186/t-test |
Reported exacerbations# (n, 2003-1980) | 0 | 3 | P < 0.001/U-test |