Mutations in the C-terminal region of the HIV-1 reverse transcriptase and their correlation with drug resistance associated mutations and antiviral treatment

Table 3 Association of selected C-terminal mutations with antiretroviral treatment (*)

Position according to HXB2 (*²)	Current antiretroviral treatment [p = ]	Current NRTI- treatment [p = ]	Current AZT- treatment [p = ]	Prior AZT- treatment [p = ]	AZT- treatment six months prior to sample- taking [p = ]
369	0.173	0.318	1	0.380	0.015
395	0.154	0.481	0.670	0.283	0.054
399	0.007	0.012	0.455	0.075	0.019
520	0.051	0.134	1	0.142	0.086
524	0.185	0.156	0.024	0.731	0.061
554	0.816	0.052	0.046	0.077	0.024

* Only the p-values of mutations that are either statistical associated or showing the tendency to be associated with antiretroviral treatment are shown
*² All replacements that occurred at the indicated sites were included in the statistic analysis

ISSN: 2047-783X