Skip to main content

Table 1 Table 1

From: GNAS1 T393C polymorphism and disease progression in patients with malignant melanoma

  All TT TC CC P
N (%) 328 69 (21.0) 149 (45.4) 110 (33.5)  
Gender (m/f) 167/161 30/39 86/63 51/59 0.074
Mean age at diagnosis 54.2 55.0 54.4 53.4 0.517
UICC Category.      
I 202 (61.6) 45 (22.3) 85 (42.1) 72 (35.6)  
II 72 (22.0) 13 (18.1) 34 (47.2) 25 (34.7)  
III 47 (14.3) 9 (19.1) 30 (63.8) 8 (17.0)  
IV 7 (2.1) 2 (28.6) 0 (0) 5 (71.4) 0.683
Type      
SSM 153 31 71 51  
NM 38 8 16 14  
LMM 34 9 14 11  
ALM 30 7 16 7  
UCM 73 14 32 27  
Tumor thickness (mm)      
<0,75 191 (58.2) 40 (20.9) 80 (41.9) 71 (37.2)  
0,75-1,5 55 (16.8) 14 (25.5) 27 (49.1) 14 (25.5)  
1,5- 4 58 (17.7) 8 (13.8) 31 (53.4) 19 (32.8)  
> 4 24 (7.3) 7 (29.2) 11 (45.8) 6 (25.0) 0.385
Clark level      
I 51 (15.5) 10 (19.6) 22 (43.1) 19 (37.3)  
II 40 (12.2) 10 (25.0) 15 (37.5) 15 (37.5)  
III 114 (34.8) 24 (21.1) 50 (43.9) 40 (35.1)  
IV 92 (28.0) 20 (21.7) 45 (48.9) 27 (29.1)  
V 10 (3.0) 2 (20.0) 6 (60.0) 2 (20.0) 0.333
Node      
0 305 (93.0) 66 (21.6) 135 (44.3) 104 (34.1)  
1 13 (4.0) 3 (23.1) 6 (46.2) 4 (30.8)  
2 10 (3.0) 0 (0) 8 (80.0) 2 (20.0) 0.865
Distant metastasis      
No 321 (97.9) 67 (20.9) 149 (46.4) 105 (32.7)  
Yes 7 (2.1) 2 (28.6) 0 (0,0) 5 (71.4) 0.266
  1. M; male; f, female; SSM, superficial spreading melanoma; NM, nodular melanoma; LMM, lentigo maligna melanoma; ALM, acral lentiginous melanoma; UCM, unclassified melanoma