Skip to main content

Table 2 Multivariable Cox proportional hazard model for metastasis in 328 patients with malignant melanoma

From: GNAS1 T393C polymorphism and disease progression in patients with malignant melanoma

   Metastasis  
  Hazard ratio 95% CI P
Age at diagnosis 1.0 0.98-1.02 0.802
Gender    
   Male 1*   
   Female 0.96 0.61 - 1.53 0.866
UICC Stage    
   I 1*   
   II 1.91 0.96 - 3.81 0.067
   III 12.19 6.30 - 23.56 <0.001
   IV 21.47 6.03 - 76.49 <0.001
MM Type    
   SSM 1*   
   NM 1.89 0.92 - 3.88 0.081
   lMM 2.75 1.14 - 6.2 0.024
   AlM 1.56 0.74 - 3.33 0.239
   UCM 2.38 1.23 - 4.58 0.010
T393C    
   TT 1*   
   C 2.55 1.22 - 5.32 0.012
  1. *reference group. CI, confidence interval. SSM were chosen as reference because they represent the largest subgroup of melanomas. SSM, superficial spreading melanoma; NM, nodular melanoma; LMM, lentigo maligna melanoma; ALM, acral lentiginous melanoma; UCM, unclassified melanoma