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Table 2 Multivariable Cox proportional hazard model for metastasis in 328 patients with malignant melanoma

From: GNAS1 T393C polymorphism and disease progression in patients with malignant melanoma

  

Metastasis

 
 

Hazard ratio

95% CI

P

Age at diagnosis

1.0

0.98-1.02

0.802

Gender

   

   Male

1*

  

   Female

0.96

0.61 - 1.53

0.866

UICC Stage

   

   I

1*

  

   II

1.91

0.96 - 3.81

0.067

   III

12.19

6.30 - 23.56

<0.001

   IV

21.47

6.03 - 76.49

<0.001

MM Type

   

   SSM

1*

  

   NM

1.89

0.92 - 3.88

0.081

   lMM

2.75

1.14 - 6.2

0.024

   AlM

1.56

0.74 - 3.33

0.239

   UCM

2.38

1.23 - 4.58

0.010

T393C

   

   TT

1*

  

   C

2.55

1.22 - 5.32

0.012

  1. *reference group. CI, confidence interval. SSM were chosen as reference because they represent the largest subgroup of melanomas. SSM, superficial spreading melanoma; NM, nodular melanoma; LMM, lentigo maligna melanoma; ALM, acral lentiginous melanoma; UCM, unclassified melanoma
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European Journal of Medical Research

ISSN: 2047-783X

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