From: Prognostic value of hedgehog signal component expressions in hepatoblastoma patients
Prognostic factors | Shh(+) | Â | Smo(+) | Â | Gli-1(+) | Â |
---|---|---|---|---|---|---|
 |  | P |  | P |  | P |
 | n(%) |  | n(%) |  | n(%) |  |
Age(y)(n) | Â | Â | Â | Â | Â | Â |
   0-2 years(15) | 13 | 0.554 | 10 | 0.508 | 10 | 0.571 |
   2-5 years (12) | 11 |  | 8 |  | 9 |  |
   over 5 years (5) | 4 |  | 3 |  | 3 |  |
Gender | Â | Â | Â | Â | Â | Â |
   Female (10) | 9 | 0.704 | 5 | 0.148 | 7 | 0.625 |
   Male (21) | 19 |  | 16 |  | 15 |  |
Histology | Â | Â | Â | Â | Â | Â |
   Well (17) | 13 | 0.07 | 9 | 0.108 | 9 | 0.046 |
   Poorly (15) | 15 |  | 12 |  | 13 |  |
Tumor size | Â | Â | Â | Â | Â | Â |
   n ≤ 2 (3) | 2 | 0.056 | 1 | 0.070 | 1 | 0.030 |
   2 < n ≤ 5 (14) | 11 |  | 8 |  | 8 |  |
   5 < n (15) | 15 |  | 12 |  | 13 |  |
Stage | Â | Â | Â | Â | Â | Â |
   Stages I, II (8) | 5 | 0.078 | 2 | 0.010 | 1 | 0.000 |
   StagesIII, IV (24) | 23 |  | 19 |  | 21 |  |
Preoperative chemotherapy | Â | Â | Â | Â | Â | Â |
   Yes(17) | 14 | 0.350 | 8 | 0.022 | 9 | 0.046 |
   No (15) | 14 |  | 13 |  | 13 |  |
Prognosis | Â | Â | Â | Â | Â | Â |
   Survived with evidence-free (19) | 15 | 0.108 | 8 | 0.022 | 10 | 0.020 |
   Recurrence/died of disease (13) | 13 |  | 13 |  | 12 |  |