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Table 1 Clinical Characteristics of the study groups

From: Transient elastography discloses identical distribution of liver fibrosis in chronic hepatitis C between HIV-negative and HIV-positive patients on HAART

  HCV mono-infected HIV/HCV co-infected
  N = 84 N = 57
Age, median (range) 48 (21-79) 42 (23-58)
Male, n 54 49
HCV genotypes   
   1, n (%) 59 (70%) 47 (82%)
   non-1, n (%) 25 (30%) 10 (18%)
Risk factor for HCV or HIV/HCV infection   
   i.v. drug abuse, n (%) 45 (54%) 32 (56%)
   Blood products, n (%) 0 25 (44%)
   unknown, n (%) 39 (46%) 0
HAART   
   No, n (%) n.a. 10 (18%)
   Yes, n (%) n.a. 47 (82%)
PI-based HAART, n (%) n.a. 39 (84%)
CD4 count, median (range) n.d. 430 (10-1486)
CD4 < 200/μl, n (%) n.d. 8 (14%)
AST (U/l), mean ± SD 59.7 ± 42.4 66.6 ± 60.1
ALT (U/l), mean ± SD 76.3 ± 48.8 94.4 ± 84.3
GGT (U/l), mean ± SD 104.0 ± 128.0 128.0 ± 129.0
Bilirubin (mg/dl), mean ± SD 0.7 ± 0.5 1.0 ± 1.0*
Platelets (T/l), mean ± SD 198.3 ± 81.0 155.9 ± 68.4*
APRI-score†, mean ± SD 1.5 ± 2.3 2.7 ± 5.3
Metavir-Score according to transient elastography (% of patients)°
   F0/1 42 (50%) 31 (54%)
   F2 10 (12%) 5 (9%)
   F3 11 (13%) 8 (14%)
   F4 21 (25%) 13 (23%)
  1. * p < 0.05, † APRI = AST to platelet ratio. calculation of APRI-score: AST/Platelet count