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Table 2 Characteristics of treatment response.

From: Maraviroc in treatment-experienced patients with HIV-1 infection - experience from routine clinical practice

Characteristics

Group A1

(n = 25)

Group B2

(n = 7)

All patients

(n = 32)

Median duration of follow-up (months)

15

(n = 25)

21

(n = 7)

16

(n = 32)

Median duration until VL below detection limit (days)

52

(n = 24)*

-

52

(n = 24)*

Median increase in CD4+ T-cell count at month 3

112 cells/μl

(n = 25)

21 cells/μl

(n = 7)

141 cells/μl

(n = 32)

Median increase in CD4+ T-cell count at month 6

96 cells/μl

(n = 25)

88 cells/μl

(n = 7)

124 cells/μl

(n = 32)

Number of patients with VL below detection limit after 3 months

18/25

6/7**

24/32

Number of patients with sustained complete response (median duration of observation)

12

(11.5 months)

5

(14.2 months)

17

(12.1 months)

Number of patients with secondary treatment failure

(median duration to failure)

8

(9.2 months)

2

(10 months)

9

(9.2 months)

Number of patients with partial response

3

0

3

Number of patients with primary treatment failure (median duration to failure)

2

(3.5 months)

-

3

(4.0 months)

  1. *One patient never showed VL suppression (lowest VL under MVC: 1874 copies/ml).
  2. **In one case VL was detectable at month 3 despite the addition of MVC, 1HIV-RNA detectable at screening, 2HIV-RNA not detectable at screening.