Notch signaling and ghost cell fate in the calcifying cystig odontogenic tumor

Table 2 Immunoexpression of Notch receptors and ligand proteins in calcifying cystic odontogenic tumors (n = 5)

CCOT components	*Notch1*	*Notch2*	*Notch3*	*Notch4*	*Jagged1*	*Jagged2*	*Delta1*
Basal pre-ameloblast-like cells	+	-	-	+	-	-	-
Suprabasal stellate reticulum-like cells	+	-	-	+	+	-	-
Transitory squamous cells	+	-	-	+	+	-
Ghost cells	2+	-	-	+	3+	-	-
Calcifications	+	-	+	+	+	-	-
Connective tissue stroma	-	-	+	+	-	-	-
Dentinoid	NA	NA	NA	NA	NA	NA	NA
Odontome	NA	NA	NA	NA	NA	NA	NA

CCOT, Calcifying cystic odontogenic tumor; -, negative; +, mild (< 25% positivity); 2+, moderate (25-50% positivity); 3+, strong (> 50% positivity); NA, Not available

ISSN: 2047-783X