Table 1 Baseline data and histological findings of 118 patients with histologically proven non-alcoholic fatty liver disease (NAFLD) and 18 lean controls. Data is presented as mean (SD)
Variable | Lean Controls n = 18 | Simple Steatosis n = 11 | Borderline NASH n = 47 | Definite NASH n = 53 | NASH Cirrhosis n = 7 |
|---|---|---|---|---|---|
Gender | |||||
Male, n | 11 | 7 | 31 | 36 | 5 |
Female, n | 7 | 4 | 16 | 17 | 2 |
Age, yr | 44.0 (10) | 51.0 (12) | 50.5 (12) | 49.5 (12) | 59.0 (6) |
BMI, kg/m 2 | 24.4 (2.3) | 24.6 (4.6) | 27.4 (7.2) | 30.3 (6.3)a | 31.1 (4.6)a |
Serum ALT, U/l | 26 (8) | 41 (12) | 67 (40)a | 94 (64)aa | 64 (30)a |
Cholesterol, mg/dl | 172 (12) | 243 (39) | 235 (47) | 216 (49) | 189 (48) |
Triglycerides, mg/dl | 136 (17) | 142 (75) | 239 (1172) | 211 (127) | 185 (118) |
Impaired glucose tolerance, n | 0 | 0 | 15 | 21 | 2 |
Diabetes mellitus Type 2, n | 0 | 2 | 9 | 5 | 3 |
Fibrosis score, n | |||||
F 0 | - | 9 | 11 | 2 | - |
F 1 | - | 1 | 29 | 28 | - |
F 2 | - | 1 | 3 | 10 | - |
F 3 | - | 0 | 4 | 13 | - |