|  |  | General features |  |  |  | Kidney |  | Blood |  | Urine |  |  |  |  |  |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Code | Markers Strata | N* | Age | BMI kg/(m) 2 | Systolic BP mm Hg | Diastolic BP mm Hg | ASFP score | C-Cr** ml/min | HCO 3 mM-l"' | pH | pH | Volume ml | Na+K mM DG | SS-UA | SS-CaOx DG | SS-HAP DG |
A | P-UA | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 |    L 307(4) | 78 | 43(1) | 26.0(0.3) | 126(2)[65] | 81(1)[65] | 33(3) | 112(3) | 23.6(0.2) | 7.40(0.0) | 6.23 (0.09) | 246(18) | 21(0.8) | 4.5(0.2)[74] | 0.9(0.1)[74] | 3.6(0.3)[74] |
 |    H 408(6) | 76 | 40(1) | 26.6(0.3) | 128(2)[65] | 83(1)[65] | 41(5) | 110(2) | 23.3(0.3) | 7.40(0.0) | 6.02(0.09) | 195(15) | 20(1.1) | 5.3(0.2)171] | 1.1(0.1)[71] | 2.2(0.4)[71] |
 |    p <0.001 |  | 0.11 | 0.07 | 0.34 | 0.22 | 0.09d | 0.23 | 0.18 | 0.37 | 0.04 | 0.02 | 0.08 | 0.002 | 0.2 | 0.003 |
B | U-MDA | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 |    L 89(2) | 77 | 40(1) | 26.2(0.3) | 124(2)[65] | 80(1)[65] | 37(5) | 112(2) | 23.1(0.3) | 7.40(0.0) | 6.05(0.09) | 162(13) | 18(0.7) | 5.2(0.2) | 1.3(0.1) | 3.1(0.4) |
 |    H 173(5) | 77 | 43(1) | 26.4(0.3) | 130(3)165] | 85(2)[65] | 37(3) | 110(2) | 23.9(0.2) | 7.41(0.0) | 6.20(0.09) | 280(18) | 23(1.1) | 4.5(0.2) | 0.6(0.1) | 2.7(0.3) |
 |    p <0.001 |  | 0.03 | 0.26 | 0.03 | 0.01 | 0.32d | 0.23 | 0.02 | 0.005 | 0.13 | <0.001 | 0.001 | 0.003 | < 0.001 | 0.19 |
C | U-MDA/P-UA | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 |    I. 244(7) | 77 | 40(1) | 26.3(0.3) | 124(2)[65] | 81(1)[65] | 36(5) | 112(2) | 23.1(0.3) | 7.40(0.0) | 6.04(0.09) | 151(12) | 18(0.7) | 5.2(0.2)[74] | 1.4(0.])[74] | 3.1(0.4)[74] |
 |    H 519(18) | 77 | 43(1) | 26.4(0.4) | 130(2)[65] | 84(1)[65] | 37(3) | 110(2) | 23.8(0.2) | 7.41(0.0) | 6.21(0.08) | 291(18) | 23(1.2) | 4.5(0.2)[71] | 0.6(0.1)[74] | 2.7(0.3)[71] |
 |    P <0.001 |  | 0.11 | 0.32 | 0.06 | 0.05 | 0.31d | 0.29 | 0.02 | 0.01 | 0.08 | < 0.001 | 0.001 | <0.001 | 0.001 | 0.19 |
D | U-NIT | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 |    L 85(3) | 59 | 43(1) | 26.4(0.3) | 126(3)[52] | 81(2)[52] | 38(5) | 109(3) | 23.0(0.3) | 7.40(0.0) | 6.13(0.10) | 184(16) | 19(1.0) | 5.0(0.2)[52] | 1.3(0.2)[52] | 3.5(0.4)[52] |
 |    H 184(11) | 58 | 42(1) | 26.5(0.3) | 127(3)[48] | 83(2)[48] | 35(4) | 115(3) | 23.4(0.2) | 7.40(0.0) | 6.20(0.10) | 278(22) | 22(1.3) | 4.5(0.2)[57] | 0.7(0.2)[571 | 2.3(0.4)[57] |
 |    P <0.001 |  | 0, 43 | 0.41 | ,0.39 | 0.26 | 0.31d | 0.09 | 0.19 | 0.41 | 0.33 | < 0.001 | 0.04 | 0.04 | 0.004 | 0.02 |
E | U-NIT/P-UA | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 |    L 247(10) | 59 | 41(1) | 26.4(0.3) | 126(3)L54J | 81(2)[54] | 36(5) | 111(3) | 23.1(0.1) | 7.40(0.0) | 6.11(0.109) | 184(16) | 19(0.9) | 5.0(0.2)[53] | 1.2(0.2)[53] | 3.2(0.4)[53] |
 |    H 533(35) | 58 | 44(1) | 26.5(0.4) | 127(3)[46] | 83(2)[46] | 37(5) | 113(3) | 23.3(0.2) | 7.40(0.0) | 6.23(0.10) | 278(22) | 21(1.3) | 4.4(0.2)[56] | 0.7(0.2)[56] | 2.5(0.4)[56] |
 |    p < 0.001 |  | 0.13 | 0.42 | 0.42 | 0.22 | 0.34d | 0.34 | 0.37 | 0.49 | 0.20 | < 0.001 | 0.11 | 0.03 | 0.008 | 0.10 |
2b. Additional data (urine, plasma, urine/plasma) from the same IRCU padcnts as organized in Table 2a. Data are mean (SE). For further informations see footnotes, Table 2a and text. | ||||||||||||||||
 |  | Urine |  |  |  |  |  |  |  | Plasma |  |  |  | Urine (U)/Plasma (P) |  |  |
Code | Markers Strata | N-AIb-P mg | Ca mM | Pi mM | Ca/Pi mM/mM | (Ca/Pi)/Cit 1/mM | (Ca/Pi)/Mg 1/mM | N-Alb-P 1 -1 | N-Alb-P g 1 -1 | PTH pg ml -1 | Ca mM-1 -1 | Pi mM-1 -1 | Ca/Pi mM/mM | U M /P M * | U NP /P NP ** | Â |
A | P-UA | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 | L | 8.4(2.4) | 0, 35(0, 02) | 1, 3(0.07) | 0, 40(0, 06) | 0.32(0.04) | 0, 32(0, 03) | 40(8)[75] | 23.1(0.5) | 26(1) | 2.34(0.01) | 1.01(0.02) | 2, 45(0.04) | 0.16(0.02) | 1.68(0.3)[75] |  |
 |    H | 4, 0(0.6) | 0, 29(0.02) | 1, 2(0.09) | 0.38(0.05) | 0.32(0.06) | 0, 32(0.06) | 28(3)[73] | 24.5(0.5) | 28(2) | 2.34(0, 01) | 1.01(0.02) | 2.45(0.05) | 0.16(0, 02) | 1.19(0.1)173) |  |
 |    P | 0.005 d | 0.01 | 0, 17 | 0, 37 | 0.21 | 0, 20 | 0.16 | 0.03 | 0, 13 | 0, 29 | 0, 46 | 0, 50 | 0.39 | 0.08d |  |
B | U-MDA | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 |    L | 3.5(0.6) | 0.31(0.02) | 1.18(0.07) | 0.40(0.05) | 0, 26(0.03) | 0, 24(0.03) | 32(3)[75] | 23.4(05) | 29(2) | 2.35(0.01) | 1.00(0.02) | 2.49(0.05) | 0.16(0.02) | 1.42(0.1)[74] |  |
 |    H | 8.9(2.4) | 0, 33(0.02) | 1.31(008) | 0.39(0.06) | 0.33(0.07) | 040(0.06) | 36(8)[73] | 24.2(0.5) | 25(1) | 2, 33(0, 01) | 1, 02(0.02) | 2.42(0.04) | 0.16(0.02) | 1, 45(0 3)[74] |  |
 |    p | 0.001d | 0.23 | 0.11 | 0.42 | 0.03d | 0.001d | 0.14 | 0.14 | 0.04 | 0.21 | 0.16 | 0.13 | 0.49 | 0.09d |  |
C | U-MDA/P-UA | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 |    L | 3.5(0.5) | 0.30(0.02) | 1.13(0.08) | 0.40(0.05) | 0.26(0.09) | 0.25(0.03) | 32(3)[75] | 23.7(0.5) | 28(1) | 2.35(0.01) | 1.00(0.02) | 2.49(0, 04) | 0.16(0.02) | 1.41(0, 1)[74] |  |
 |    H | 8.9(2.4) | 0.35(0.02) | 1.35(0.08) | 0.39(0.06) | 0.39(0.04) | 039(0.06) | 36(8)[731 | 23.8(0.5) | 26(1) | 2, 33(0.01) | 1.02(0, 02) | 2.42(0.05) | 0.16(0.02) | 1.46(0.3)[74] |  |
 |    p | 0.001 d | 0.03 | 0.02 | 0.42 | 0.005 | 0.00 l d |  | 0.43 | 0.12 | 0.14 | 0.19 | 0.14 | 0.49 | 0.16d |  |
D | U-Nit | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 |    L | 68(2.8) | 0.32(0.03) | 1.21(0.09) | 0.39(0.05) | 0.24(0.03) | 0.28(0.03) | 39(8)[57] | 23.9(0 7) | 30(2) | 235(0.02) | 0.97(0.02) | 2.54(0.05) | 0.15(0.02) | 1.65(0.3)[57] |  |
 |    H | 6.7(1.8) | 0.34(0.02) | 1.25(0.09) | 0.39(0.06) | 0.43(0.09) | 0.39(0.07) | 30(7)[56] | 23.0(0.6) | 26(2) | 2 33(0.01) | 1.05(0.02) | 2.35(0.05) | 0.17(0.02) | 1.31(0.2)[56] |  |
 |    p | 0.1011 | 0.32 | 0, 37 | 48 | 0.02 d | 007d | 009d | 0.18 | 0.05 | 0.12 | 0.005 | 0.004 | 0.32 | 0.14d |  |
E | U-Nit/P-UA | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 |    L | 6.2(2.8) | 0.32(0.03) | 1.12(0.09) | 0.47(0.06) | 0.33(0.07) | 0.36(0.07) | 37(8)[57] | 23.9(0, 7) | 30(2) | 236(0.02) | 0.99(0.02) | 2.53(0.05) | 0.18(0.02) | 59(0.3)[56] |  |
 |    H | 7, 4(1.8) | 0.34(0.02) | 1.34(6.09) | 0.31(0.07) | 0.34(0.06) | 0.31(0 04) | 33(7)[56] | 22.9(0.6) | 26(1) | 2.32(0.01) | 1.04(0.02) | 2.36(0.05) | 0.14(0.01) | 1.37(0.2)[57J |  |
 |    p | 0.04 d | 0.3 | 0.04 | 0.01 | 0.19 | 0.5 | 0.24 | 0.14 | 0.06 | 0.005 | 0.04 | 0.01 | 0.04 | 0.32d |  |