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Table 1 Logistic regression analyses of genotype frequencies of SNPs GSTP1 (rs1695), GSTA1 and deletion in GSTM1 and GSTT1 in colorectal cancer cases and controls from a Czech population

From: Common polymorphisms in GSTM1, GSTT1, GSTP1, GSTA1 and susceptibility to colorectal cancer in the Central European population

  

Control

CRC

   
  

N

%

N

%

OR***

95% Cl

P-value

GSTA1 (C69T)

CC

76

34.8

69

35,0

1.00

 

0.981*

 

CT

108

49.5

99

50.3

1.04

(0.67–1.60)

0.847**

 

TT

34

15.6

29

14.7

1.03

(0.56–1.90)

0.960**

 

Trend

218

 

197

 

1.02

(0.76–1.37)

0.887*

GSTT1 _del

wt

179

82.1

157

79.7

1.00

 

0.531*

 

del

39

17.9

40

20.3

1.13

(0.69–1.86)

0.711**

 

Trend

218

 

197

 

1.13

(0.69–1.86)

0.531*

GSTM1 _del

wt

117

53.7

97

49.2

1.00

 

0.262*

 

del

101

46.3

100

50.7

1.25

(0.84–1.86)

0.276**

 

Trend

218

 

197

 

1.25

(0.84–1.86)

0.263*

GSTP1 (Ile105Val,rs1695)

AA

93

42.6

103

52.3

1

 

0.095*

 

AG

100

45.9

74

37.6

0.64

(0.420.98)

0.043**

 

GG

25

11.5

20

10.2

0.67

(0.35–1.28)

0.266**

 

Trend

218

 

197

 

0.76

(0.56–1.02)

0.062*

  1. *LR-test.
  2. **Wald’s test.
  3. ***Age and sex adjusted.