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Table 5 Correlation between serum UA, NO, ET-1, and NO/ET-1 ratio as well as P CIPA , SOD, MDA, CRP, ox-LDL, and LDL

From: RETRACTED ARTICLE: Effects of uric acid on endothelial dysfunction in early chronic kidney disease and its mechanisms

  Serum uric acid (μmol/L) Serum NO (μmol/L) Serum ET-1 (pg/mL) NO/ET-1 ratio PCIPA(%)
  r value P value r value P value r value P value r value P value r value P value
SOD (U/mL) −0.6885 0.0277 0.8179 0.0038 −0.7793 0.0079 0.8143 0.0041 −0.8180 0.0000
MDA (nmol/mL) 0.8195 0.0037 −0.9171 0.0002 0.8658 0.0012 −0.9143 0.0002 0.8015 0.0053
CRP (μg/mL) 0.7251 0.0177 −0.7554 0.0115 0.7447 0.0135 −0.8042 0.0050 0.6752 0.0322
ox-LDL (mmol/L) 0.8479 0.0019 −0.7459 0.0132 0.7900 0.0065 −0.7949 0.0060 0.5266 0.1179
LDL (mmol/L) 0.6356 0.0483 −0.5080 0.1339 0.5734 0.0831 −0.4947 0.1460 0.5902 0.0725
  1. Note: NO as dependent variable and SOD, MDA, CRP, ox-LDL, LDL as independent variables, multiple stepwise regression analysis showed that serum SOD and CRP entered the equation, and the equation was y = 0.315 × 1-0.802 × 2-22.120 (y = NO, ×1 = SOD, ×2 = CRP; -22.120 was a constant). ET-1 as dependent variable and SOD, MDA, CRP, ox-LDL, and LDL as independent variables, multiple stepwise regression analysis showed that serum ox-LDL and SOD entered the equation, and the equation was y = 0.051 × 1-0.082 × 2 + 22.517 (y = ET-1, ×1 = ox-LDL, ×2 = SOD; 22.517 was a constant). NO/ET-1 ratio as dependent variable and SOD, MDA, CRP, ox-LDL, LDL as independent variables, multiple stepwise regression analysis showed that serum SOD and CRP entered the equation, and the equation was y = 0.102 × 1-0.316 × 2-13.151 (y = NO/ET-1 ratio, ×1 = SOD, ×2 = CRP; 13.151 was a constant). PCIPA as dependent variable and SOD, MDA, CRP, ox-LDL, LDL as independent variables, multiple stepwise regression analysis showed that serum SOD entered the equation, and the equation was y = 111.437-0.397 × 1 (y = PCIPA, ×1 = SOD; 111.437 was a constant).