Figure 4
A case with membranous nephropathy (MN) and diabetic nephropathy (DN). (A) Deposits of mainly IgG collected in the basement membrane and appeared as a diffuse granular pattern as shown by immunofluorescence (IF, 200×). (B) Light microscopy showing membranous glomerulonephritis in which the capillary loops were thickened and prominent. Numerous granular dense deposits were located in subepithelial areas (PAS, 200×). (C) Thickened glomerular basement membrane (GBM) with numerous granular, dense deposits located in subepithelial areas (EM, 5000×). DN, diabetic nephropathy; GBM, glomerular basement membrane; IF, immunofluorescence; IgG, immunoglobulin G; MN, membranous nephropathy; PAS, periodic acid-Schiff.