| |
1 year post-transplant
|
5 years post-transplant
|
|---|
|
Anemic
|
Non-anemic
|
P value
|
Anemic
|
Non-anemic
|
P value
|
|---|
| |
(n = 15)
|
(n = 125)
|
(n = 23)
|
(n = 95)
|
|---|
|
Age (years)
|
38 ± 11.8
|
38.9 ± 10.3
|
0.744
|
40.3 ± 9.1
|
42.3 ± 10.2
|
0.385
|
|
Gender (male/female)
|
10/5
|
88/37
|
0.766
|
16/7
|
69/26
|
0.769
|
|
BUN (mmol/L)
|
10.8 ± 6.1
|
6.9 ± 2.0
|
0.001
|
13.5 ± 8.1
|
7.1 ± 2.2
|
<0.001
|
|
Creatinine (mg/dL)
|
1.8 ± 0.6
|
1.3 ± 0.3
|
0.001
|
2.0 ± 0.8
|
1.3 ± 0.2
|
<0.001
|
|
Ccr
|
|
Mean
|
51.1 ± 20.8
|
69.1 ± 17.3
|
<0.001
|
48.1 ± 21.9
|
65.8 ± 13.7
|
<0.001
|
|
>75 mL/min/1.73 m2
|
2 (13.3%)
|
40 (32%)
|
0.136
|
4 (17.4%)
|
25 (26.3%)
|
0.372
|
|
50 to 75 mL/min/1.73 m2
|
4 (26.7%)
|
70 (56%)
|
0.032
|
4 (17.4%)
|
61 (64.2%)
|
<0.001
|
|
<50 mL/min/1.73 m2
|
9 (60%)
|
15 (12%)
|
<0.001
|
15 (65.2%)
|
9 (9.5%)
|
<0.001
|
|
Immunosuppression
|
|
Tac/CsA
|
3/12
|
30/95
|
0.73
|
3/20
|
28/67
|
0.108
|
|
MMF/AZT
|
12/3
|
110/15
|
0.382
|
21/2
|
81/14
|
0.448
|
|
ACEI or ARB (yes/no)
|
1/14
|
19/106
|
0.372
|
5/18
|
16/79
|
0.58
|
|
Iron medicine (yes/no)
|
11/4
|
12/113
|
<0.001
|
17/6
|
6/89
|
<0.001
|
- ARB, angiotensin receptor blockers; ACEI, angiotensin-converting-enzyme inhibitors; AZT, azathioprine; BUN, blood urea nitrogen; Ccr, calculated creatinine clearance; CsA, cyclosporin A; MMF, mycophenolate mofetil; Tac, tacrolimus.
