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Table 1 Functional enrichment of differentially expressed genes between metastatic samples, non-metastatic samples and non-malignant samples ( P< 0.05)

From: RETRACTED ARTICLE: Establishing an osteosarcoma associated protein-protein interaction network to explore the pathogenesis of osteosarcoma

Category Term Count P-value Genes
GO:0002822 Regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 4 0.01166 C3, TBX21, RARA, FOXP3
GO:0002819 Regulation of adaptive immune response 4 0.01225 C3, TBX21, RARA, FOXP3
GO:0016071 mRNA metabolic process 9 0.01427 HNRNPL, NCBP2, UPF3A, C17ORF71, RNMT, GTF2F1, SYNCRIP, SNRPC, SF3A1
GO:0044092 Negative regulation of molecular function 8 0.02485 MDFI, KDM1A, ADCY2, RGS3, WWP2, BUB1B, FOXP3, ANGPTL4
GO:0000184 Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 3 0.02712 NCBP2, UPF3A, C17ORF71
GO:0007626 Locomotory behavior 7 0.03055 HRAS, CCR3, SEMA3F, MYO15A, CHRNA4, SEMA3A, ESPN
GO:0051129 Negative regulation of cellular component organization 5 0.03381 SEMA3F, RDX, CLASP2, SEMA3A, FOXP3
GO:0048841 Regulation of axon extension involved in axon guidance 2 0.03386 SEMA3F, SEMA3A
GO:0048843 Negative regulation of axon extension involved in axon guidance 2 0.03386 SEMA3F, SEMA3A
GO:0006370 mRNA capping 2 0.03386 NCBP2, RNMT
GO:0000956 Nuclear-transcribed mRNA catabolic process 3 0.03609 NCBP2, UPF3A, C17ORF71
GO:0045621 Positive regulation of lymphocyte differentiation 3 0.03609 RARA, INPP5D, AP3B1
GO:0051249 Regulation of lymphocyte activation 5 0.03845 TBX21, RARA, INPP5D, FOXP3, AP3B1
GO:0009452 RNA capping 2 0.04215 NCBP2, RNMT
GO:0050919 Negative chemotaxis 2 0.04215 SEMA3F, SEMA3A