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Table 2 Distribution of dopamine replacement therapy according to patient age a

From: The impact of extended release dopamine agonists on prescribing patterns for therapy of early Parkinson’s disease: an observational study

Patient age

Therapy

2007

Year 2011

Age <65 years

DA monotherapy, n (%)

10 (50%)

14 (61%)

Daily LD equivalents, mg (mean ± SD)

245 ± 52

281 ± 48

 

LD monotherapy, n (%)

3 (15%)

2 (9%)

Daily mg (mean ± SD)

274 ± 29

275 ± 15

 

DA + LD combined therapy, n (%)

7 (35%)

7 (30%)

Total daily LD equivalents, mg (mean ± SD)

385 ± 62

388 ± 70

Age between 65 and 75 years

DA monotherapy, n (%)

4 (14%)

14 (45%)b

Daily LD equivalents, mg (mean ± SD)

250 ± 57

314 ± 53b

 

LD monotherapy, n (%)

11 (37%)

2 (6%)b

Daily dose, mg (mean ± SD)

325 ± 50

350 ± 25

 

DA + LD combined therapy, n (%)

14 (47%)

15 (49%)

Total daily LD equivalents, mg (mean ± SD)

425 ± 40

415 ± 54

Age >75 years

DA monotherapy, n (%)

0 (0%)

1 (6%)

Daily LD equivalents, mg (mean ± SD)

 

250 ± 0

 

LD monotherapy, n (%)

4 (67%)

11 (61%)

Daily dose, mg (mean ± SD)

465 ± 28

450 ± 20

 

DA + LD combined therapy, n (%)

2 (33%)

6 (33%)

Total daily LD equivalents, mg (mean ± SD)

525 ± 25

530 ± 22

  1. aDA, dopamine agonist; LD, levodopa. bP < 0.01 compared with 2007 by χ2 statistic or unpaired Student’s t-test statistic. See Methods Section for details.