Proteomic analysis of exosomes derived from human lymphoma cells

Table 1 Categories of proteins identified in Raji cells and EXO _Raji by GO analysis

Biological process				Molecular function
	E&R	EXO _Raji	Raji cells		E&R	EXO _Raji	Raji cells
Response to stimulus	45	60	108	Hydrolase activity	39	43	82
Immune system process	18	32	16	Nucleoside binding	40	42	91
Cell killing	3	3	3	Nucleotide binding	58	60	143
Localization	46	65	77	Protein binding	105	139	250
Multi-organism process	11	20	25	Nitric-oxide synthase regulator activity	2	2	2
Establishment of localization	43	62	74	Proteasome activator activity	2	2	2
Cellular component organization	44	57	86	Nucleobase binding	2	2	3
Cellular component biogenesis	23	27	58	Cell surface binding	4	5	4
Cell component				Carboxylic acid binding	5	5	7
	E&R	EXO _Raji	Raji cells	Translation factor activity	5	5	10
Ribonucleo protein complex	8	10	61	Lyase activity	8	8	11
Protein complex	47	52	98	Cofactor binding	9	9	15
Organelle lumen	24	24	100
Non-membrane bounded	45	51	113
Organelle part	52	56	162
Intracellular organelle	86	105	241
Intracellular part	107	139	292
Organelle membrane	14	17	33
Vesicle	24	32	34
Organelle envelope	11	14	34

The protein constituents of Raji cell and EXO_Raji were analyzed by GO software according to the biological pathways, molecular function, and cell components. Table 1 shows the analysis results. The numbers of protein kinds presented in each sample or in both samples were listed.

ISSN: 2047-783X