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Table 5 TNF-α polymorphisms (GG + GA vs. AA) and susceptibility to lung cancer by subgroup analyses of region and detection method

From: RETRACTED ARTICLE: Meta-analysis of the associations between TNF-α or IL-6 gene polymorphisms and susceptibility to lung cancer

   N I 2 P value for heterogeneity OR (95% CI) Z P
Region Europe 5 12.2 0.336 1.40 (0.70 to 2.78) 0.95 0.342
Asia 1    0.12 (0.03 to 0.54) 2.77 0.006
Detection method Real-time PCR 1    1.27 (0.30 to 5.39) 0.33 0.743
PCR-RFLP 4 54.5 0.086 0.60 (0.15 to 2.38) 0.73 0.465
PCR-SSP 1    10.57 (0.58 to 192.90) 1.59 0.112
  1. PCR: polymerase chain reaction; PCR-RFLP: polymerase chain reaction-restriction fragment length polymorphism; PCR-SSP: polymerase chain reaction-sequence specific primer; N: number of enrolled studies; OR: odds ratio; 95% CI: 95% confidence interval.