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Table 5 TNF-α polymorphisms (GG + GA vs. AA) and susceptibility to lung cancer by subgroup analyses of region and detection method

From: RETRACTED ARTICLE: Meta-analysis of the associations between TNF-α or IL-6 gene polymorphisms and susceptibility to lung cancer

  

N

I 2

P value for heterogeneity

OR (95% CI)

Z

P

Region

Europe

5

12.2

0.336

1.40 (0.70 to 2.78)

0.95

0.342

Asia

1

  

0.12 (0.03 to 0.54)

2.77

0.006

Detection method

Real-time PCR

1

  

1.27 (0.30 to 5.39)

0.33

0.743

PCR-RFLP

4

54.5

0.086

0.60 (0.15 to 2.38)

0.73

0.465

PCR-SSP

1

  

10.57 (0.58 to 192.90)

1.59

0.112

  1. PCR: polymerase chain reaction; PCR-RFLP: polymerase chain reaction-restriction fragment length polymorphism; PCR-SSP: polymerase chain reaction-sequence specific primer; N: number of enrolled studies; OR: odds ratio; 95% CI: 95% confidence interval.