Table 2 Main results in the total and subgroup analysis
Analysis model | Study groups | n | Random-effect model | Fixed-effect model | Heterogeneity | |
|---|---|---|---|---|---|---|
OR (95% CI) | OR (95% CI) | χ 2 | P | |||
C vs. T | Total analysis | 12 | 1.25 (1.04 to 1.51) | 1.23 (1.11 to 1.37) | 33.46 | 0.000 |
PB | 6 | 1.22 (1.05 to 1.42) | 1.22 (1.05 to 1.42) | 1.49 | 0.914 | |
HB | 6 | 1.30 (0.90 to 1.90) | 1.25 (1.08 to 1.44) | 31.93 | 0.000 | |
ESCC | 9 | 1.18 (1.00 to 1.39) | 1.17 (1.04 to 1.32) | 14.48 | 0.070 | |
South China | 3 | 0.93 (0.76 to 1.14) | 0.93 (0.76 to 1.14) | 0.71 | 0.702 | |
North China | 9 | 1.38 (1.12 to 1.70) | 1.37 (1.21 to 1.55) | 22.21 | 0.005 | |
CC vs. TT | Total analysis | 12 | 1.42 (0.99 to 2.04) | 1.42 (1.15 to 1.75) | 29.24 | 0.002 |
PB | 6 | 1.38 (1.02 to 1.88) | 1.38 (1.02 to 1.88) | 0.45 | 0.994 | |
HB | 6 | 1.46 (0.70 to 3.04) | 1.45 (1.09 to 1.93) | 28.75 | 0.000 | |
ESCC | 9 | 1.29 (0.94 to 1.77) | 1.27 (1.00 to 1.62) | 12.34 | 0.137 | |
South China | 3 | 0.82 (0.54 to 1.25) | 0.82 (0.54 to 1.24) | 1.26 | 0.531 | |
North China | 9 | 1.72 (1.16 to 2.56) | 1.73 (1.35 to 2.22) | 18.97 | 0.015 | |
CC vs. CT | Total analysis | 12 | 1.09 (0.89 to 1.33) | 1.09 (0.89 to 1.32) | 10.90 | 0.452 |
PB | 6 | 1.07 (0.80 to 1.43) | 1.06 (0.80 to 1.42) | 2.93 | 0.711 | |
HB | 6 | 1.12 (0.78 to 1.59) | 1.11 (0.85 to 1.45) | 7.94 | 0.160 | |
ESCC | 9 | 1.01 (0.80 to 1.28) | 1.01 (0.80 to 1.28) | 7.91 | 0.442 | |
South China | 3 | 0.80 (0.53 to 1.21) | 0.80 (0.53 to 1.21) | 1.53 | 0.464 | |
North China | 9 | 1.19 (0.95 to 1.50) | 1.19 (0.95 to 1.50) | 6.63 | 0.577 | |
CC + CT vs. TT | Total analysis | 12 | 1.35 (1.06 to 1.72) | 1.37 (1.17 to 1.59) | 26.54 | 0.005 |
PB | 6 | 1.36 (1.10 to 1.69) | 1.36 (1.10 to 1.69) | 4.10 | 0.536 | |
HB | 6 | 1.39 (0.86 to 2.23) | 1.37 (1.11 to 1.70) | 22.44 | 0.000 | |
ESCC | 9 | 1.28 (1.04 to 1.59) | 1.28 (1.08 to 1.52) | 11.73 | 0.164 | |
South China | 3 | 0.97 (0.73 to 1.28) | 0.97 (0.73 to 1.28) | 0.11 | 0.947 | |
North China | 9 | 1.52 (1.14 to 2.02) | 1.58 (1.32 to 1.89) | 18.30 | 0.019 | |
CC vs. TT + CT | Total analysis | 13 | 1.35 (1.03 to 1.76) | 1.34 (1.13 to 1.59) | 26.94 | 0.008 |
PB | 7 | 1.41 (1.06 to 1.89) | 1.43 (1.13 to 1.81) | 8.26 | 0.219 | |
HB | 6 | 1.30 (0.79 to 2.14) | 1.25 (0.98 to 1.60) | 18.16 | 0.003 | |
ESCC | 9 | 1.14 (0.88 to 1.47) | 1.12 (0.90 to 1.40) | 10.22 | 0.250 | |
South China | 3 | 0.82 (0.56 to 1.20) | 0.81 (0.56 to 1.19) | 1.63 | 0.443 | |
North China | 10 | 1.55 (1.17 to 2.06) | 1.53 (1.26 to 1.86) | 17.20 | 0.046 | |