Table 4 Multivariate regression analysis of infection following liver transplantation after exclusion of non-significant parameters in univariate analysis
Parameter | Group 1, n = 56 (open drain) | Group 2, n = 200 (closed drain) | p value (univariate) | p value (multivariate) |
|---|---|---|---|---|
Overall infection rate | 44 (79Â %) | 98 (49Â %) | 0.001 (s) | 0.032 (S) |
Wound infection rate | 9 (16 %) | 21 (11 %) | 0.2 (ns) | – |
Cholangitis | 2 (4 %) | 3 (1.5 %) | 0.3 (ns) | – |
Gastrointestinal infection | 1 (2 %) | 6 (3 %) | 0.5 (ns) | – |
MRSA | 1 (2 %) | 0 | 0.2 (ns) | – |
Clostridium | 1 (2 %) | 7 (3.5 %) | 0.5 (ns) | – |
Sepsis | 1 (2 %) | 10 (5 %) | 0.3 (ns) | – |
Oral candidiasis | 1 (2 %) | 2 (1 %) | 0.5 (ns) | – |
Central venous catheter infection | 8 (14 %) | 32 (16 %) | 0.5 (ns) | – |
Herpes simplex infection | 14 (25 %) | 47 (24 %) | 0.5 (ns) | – |
CMV infection | 10 (18 %) | 36 (18 %) | 0.6 (ns) | – |
Epstein-Barr virus | 0 | 1 (0.5 %) | 0.8 (ns) | – |
CoNS | 29 (52 %) | 90 (45 %) | 0.2 (ns) | – |
ESBL-producing Enterobacteriacae | 11 (20 %) | 22 (11 %) | 0.7 (ns) | – |
Overall abdominal infection rate | 28 (50Â %) | 45 (22.5Â %) | 0.001 (s) | 0.021 (S) |
Candida albicans infection rate (abdomen) | 23 (41Â %) | 39 (19.5Â %) | 0.02 (s) | 0.036 (S) |
Aspergillus spp. | 2 (4 %) | 1 (0.5 %) | 0.1 (ns) | – |
Other | 3 (5 %) | 5 (3 %) | 0.2 (ns) | – |