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Table 4 Multivariate regression analysis of infection following liver transplantation after exclusion of non-significant parameters in univariate analysis

From: Impact of abdominal drainage systems on postoperative complication rates following liver transplantation

Parameter Group 1, n = 56 (open drain) Group 2, n = 200 (closed drain) p value (univariate) p value (multivariate)
Overall infection rate 44 (79 %) 98 (49 %) 0.001 (s) 0.032 (S)
Wound infection rate 9 (16 %) 21 (11 %) 0.2 (ns)
Cholangitis 2 (4 %) 3 (1.5 %) 0.3 (ns)
Gastrointestinal infection 1 (2 %) 6 (3 %) 0.5 (ns)
MRSA 1 (2 %) 0 0.2 (ns)
Clostridium 1 (2 %) 7 (3.5 %) 0.5 (ns)
Sepsis 1 (2 %) 10 (5 %) 0.3 (ns)
Oral candidiasis 1 (2 %) 2 (1 %) 0.5 (ns)
Central venous catheter infection 8 (14 %) 32 (16 %) 0.5 (ns)
Herpes simplex infection 14 (25 %) 47 (24 %) 0.5 (ns)
CMV infection 10 (18 %) 36 (18 %) 0.6 (ns)
Epstein-Barr virus 0 1 (0.5 %) 0.8 (ns)
CoNS 29 (52 %) 90 (45 %) 0.2 (ns)
ESBL-producing Enterobacteriacae 11 (20 %) 22 (11 %) 0.7 (ns)
Overall abdominal infection rate 28 (50 %) 45 (22.5 %) 0.001 (s) 0.021 (S)
Candida albicans infection rate (abdomen) 23 (41 %) 39 (19.5 %) 0.02 (s) 0.036 (S)
Aspergillus spp. 2 (4 %) 1 (0.5 %) 0.1 (ns)
Other 3 (5 %) 5 (3 %) 0.2 (ns)
  1. Italic values indicate statistical significance of p value (p > 0.05)
  2. Group 1 open-circuit drainage (Easy Flow Drain), Group 2 closed-circuit drainage (Robinson Drainage System)