An update on the clinical diagnostic value of β-hCG and αFP for intracranial germ cell tumors

Table 3 Comparison of diagnostic sensitivity between β-hCG and αFP of CSF and blood serum in ICGCTs

	n	Old criteria (%)	New criteria (%)	P ^a
CSF β-hCG	42	23.8	59.5	0.002^*
Serum β-hCG	44	22.7	43.2	0.034^*
CSF αFP	41	9.8	17.1	0.259
Serum αFP	40	12.5	12.5	–
Total sensitivity^#	26	34.6	65.4	0.026^*

ICGCTs intracranial germ cell tumors, CSF cerebrospinal fluid, β-hCG β-subunit of human chorionic gonadotropin, αFP alpha fetoprotein
* P < 0.05; ^# recent group
^aFisher’s exact test

ISSN: 2047-783X