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Table 9 Association of superoxide dismutase levels in relation to CYP1A1 and GST gene polymorphisms in NSCLC patients and healthy controls

From: Association of CYP1A1, GSTM1 and GSTT1 gene polymorphisms with risk of non-small cell lung cancer in Andhra Pradesh region of South India

Gene Genotype Lung cancer patients (SOD levels) p value Controls (SOD levels) p value Total p value
n Mean ± SE n Mean ± SE
CYP1A1, m1 T/T 121 914.28 ± 30.05   138 1166.08 ± 12.8   0.92
  T/C 89 915.73 ± 17.03 0.45 98 1165.71 ± 13.93 0.35 0.14
  C/C 28 910.74 ± 13.57 0.62 14 1070.00 ± 37.60 0.78 0.65
CYP1A1, m2 A/A 71 922.25 ± 18.18   196 1190.00 ± 10.61   <0.01*
  A/G 156 909.87 ± 12.00 0.81 34 1165.91 ± 20.61 0.14 0.05*
  G/G 11 898.18 ± 67.01 0.07 20 1080.58 ± 23.82 0.08 0.02*
GSTM1 +/+ 174 927.01 ± 11.81   187 1214.54 ± 7.47   <0.01*
  –/– 64 875.00 ± 18.00 0.56 63 1175.71 ± 10.72 0.15 <0.01*
GSTT1 +/+ 192 929.58 ± 10.57   224 1168.03 ± 9.86   0.91
  –/– 46 843.91 ± 24.69 0.04* 26 1096.12 ± 23.16 0.10 0.05*
  1. * p < 0.05