Association of CYP1A1, GSTM1 and GSTT1 gene polymorphisms with risk of non-small cell lung cancer in Andhra Pradesh region of South India

Table 9 Association of superoxide dismutase levels in relation to CYP1A1 and GST gene polymorphisms in NSCLC patients and healthy controls

Gene	Genotype	Lung cancer patients (SOD levels)		p value	Controls (SOD levels)		p value	Total p value
Gene	Genotype	n	Mean ± SE	p value	n	Mean ± SE	p value	Total p value
CYP1A1, m1	T/T	121	914.28 ± 30.05		138	1166.08 ± 12.8		0.92
	T/C	89	915.73 ± 17.03	0.45	98	1165.71 ± 13.93	0.35	0.14
	C/C	28	910.74 ± 13.57	0.62	14	1070.00 ± 37.60	0.78	0.65
CYP1A1, m2	A/A	71	922.25 ± 18.18		196	1190.00 ± 10.61		<0.01*
	A/G	156	909.87 ± 12.00	0.81	34	1165.91 ± 20.61	0.14	0.05*
	G/G	11	898.18 ± 67.01	0.07	20	1080.58 ± 23.82	0.08	0.02*
GSTM1	+/+	174	927.01 ± 11.81		187	1214.54 ± 7.47		<0.01*
	–/–	64	875.00 ± 18.00	0.56	63	1175.71 ± 10.72	0.15	<0.01*
GSTT1	+/+	192	929.58 ± 10.57		224	1168.03 ± 9.86		0.91
	–/–	46	843.91 ± 24.69	0.04*	26	1096.12 ± 23.16	0.10	0.05*

ISSN: 2047-783X