Fig. 1
From: HDAC inhibition activates the apoptosome via Apaf1 upregulation in hepatocellular carcinoma
Expression of Apaf1 after siRNA transfection against HDAC1–3 in HLE and HLF. 48 h after transfection of siRNA against HDAC1–3, the HCC cell lines a HLE and b HLF showed a significant increased expression of Apaf1 measured by qRTPCR. c Western blot analysis of Apaf1 after siRNA showed a significant increase in Apaf1 expression compared with controls. Values are mean ± SEM, n = 3. ***p < 0.001, **p < 0.01, *p ≤ 0.05, ANOVA plus Dunnett’s posttest