Table 2 TB patients have significantly higher proportions of IFN-γ- and TNF-α-producing T cells
From: MTB-specific lymphocyte responses are impaired in tuberculosis patients with pulmonary cavities
TB (n = 46) | HCs (n = 23) | P valueb | |
|---|---|---|---|
ESAT-6 | |||
CD4 | |||
TNF-α | 2.40 (1.90–3.83) | 1.71 (1.50–2.40) | 0.0003 |
IFN-γ | 0.30 (0.20–0.70) | 0.20 (0.13–0.22) | 0.0009 |
CD8 | |||
TNF-α | 3.30 (2.20–4.23) | 1.71 (1.35–2.50) | <0.0001 |
IFN-γ | 0.65 (0.40–1.75) | 0.27 (0.14–0.70) | 0.0003 |
CP-10 | |||
CD4 | |||
TNF-α | 2.35 (0.19–0.33) | 1.99 (1.63–2.21) | 0.0254 |
IFN-γ | 0.40 (0.20–0.63) | 0.33 (0.24–0.43) | 0.0017 |
CD8 | |||
TNF-α | 2.95 (2.00–4.55) | 2.10 (1.60–2.60) | 0.0027 |
IFN-γ | 0.60 (0.15–0.52) | 0.29 (0.15–0.52) | 0.0166 |