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Table 2 TB patients have significantly higher proportions of IFN-γ- and TNF-α-producing T cells

From: MTB-specific lymphocyte responses are impaired in tuberculosis patients with pulmonary cavities

  TB (n = 46) HCs (n = 23) P valueb
ESAT-6
 CD4
  TNF-α 2.40 (1.90–3.83) 1.71 (1.50–2.40) 0.0003
  IFN-γ 0.30 (0.20–0.70) 0.20 (0.13–0.22) 0.0009
 CD8
  TNF-α 3.30 (2.20–4.23) 1.71 (1.35–2.50) <0.0001
  IFN-γ 0.65 (0.40–1.75) 0.27 (0.14–0.70) 0.0003
CP-10
 CD4
  TNF-α 2.35 (0.19–0.33) 1.99 (1.63–2.21) 0.0254
  IFN-γ 0.40 (0.20–0.63) 0.33 (0.24–0.43) 0.0017
 CD8
  TNF-α 2.95 (2.00–4.55) 2.10 (1.60–2.60) 0.0027
  IFN-γ 0.60 (0.15–0.52) 0.29 (0.15–0.52) 0.0166
  1. By Mann–Whitney, NTB non-tuberculosis, TB tuberculosis, HCs household contacts