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Table 7 Value of joint aspiration in the diagnosis of infected total hip arthroplasty

From: Prosthetic joint infection development of an evidence-based diagnostic algorithm

Author Year LoE CoR (n = x) Sensitivity Specificity Positive predictive value Negative predictive value LR for a positive result LR for a negative result
Barrack et al. 1993 I I 291       
 Aspiration culture      0.6 (0.3–0.9) 0.88 (0.84–0.92) 0.15 (0.04–0.27) 0.98 (0.97–1.0) 5.11 (1.91–11.32) 0.45 (0.1–0.83)
Mulcahy et al. 1996 I I 71       
 Aspiration culture      0.69 (0.46–0.91) 0.91 (0.83–0.99) 0.69 (0.46–0.91) 0.91 (0.83–0.99) 7.56 (2.76–61.25) 0.34 (0.09–0.65)
Williams et al. 2004 I I 273       
 Aspiration culture      0.8 (0.71–0.9) 0.94 (0.9–0.97) 0.81 (0.72–0.91) 0.93 (0.90–0.97) 12.47 (7.23–29.34) 0.21 (0.11–0.32)
Malhotra et al. 2004 I I 41       
 Aspiration culture      0.44 (0.12–0.77) 0.91 (0.81–1.0) 0.57 (0.2–0.94) 0.85 (0.73–0.97) 4.74 (0.62–106.19) 0.61 (0.23–1.09)
Schinsky et al. 2008 I I 201       
 Wbc (4.2 × 103)      0.84 (0.74–0.93) 0.93 (0.89–0.97) 0.82 (0.72–0.92) 0.94 (0.90–0.98) 12.21 (6.75–33.94) 0.18 (0.07–0.29)
 Neutrophile (80%)      0.82 (0.72–0.92) 0.83 (0.77–0.89) 0.64 (0.53–0.76) 0.92 (0.88–0.97) 4.78 (3.08–8.36) 0.22 (0.09–0.37)
Spanghel et al. 1999 I I 183       
 WBC (5.0 × 103)      0.36 (0.18–0.53) 0.99 (0.98–1.0) 0.91 (0.74–1.0) 0.9 (0.85–0.94) 55.36 (9.43–86.89) 0.65 (0.46–0.84)
 Neutrophile (80%)      0.89 (0.78–1.0) 0.85 (079–0.91) 0.52 (0.38–0.66) 0.98 (0.95–1.0) 5.94 (3.76–10.75) 0.13 (0.0–0.28)
Dinneen et al. 2013 I I 75       
 WBC (1.58 × 103)      0.895 (0.783–0.997) 0.913 (0.827–0.999) n.p. n.p. n.p. n.p.
 Neutrophile (65%)      0.897 (0.795–0.999) 0.866 (0.761–0.971) n.p. n.p. n.p. n.p.