Fig. 4From: Clinical and biometrical 12-month follow-up in patients after reconstruction of the sural nerve biopsy defect by the collagen-based nerve guide NeuromaixMechanical sensation was reduced immediately after the operation, and patients often reported “no sensation at all.” Thereafter mechanical sensitivity thresholds slightly improved, but never reached values measured at the non-operated side (a). VAS scores remained constant over time on both non-operated and operated feet (b). Vibrotactile sensation was slightly reduced after surgery (ns). In time, vibrotactile sensation recovered, but remained reduced compared to the non-operated foot (c). Blunt sensation returned quite rapid after surgery; by 1 MPO slight touch with the 10 g filament elicited in more than 50% of the patients a positive response (d). Sharp sensation recovered slower; only in the last month there was a clear improvement in the majority of patients detectable (e). Cold sensation showed a slower recovery in time, and even after 12 MPO the majority of patients were unable to sense the cold metal tip (f). Data of a–c represent mean ± SEM where */**/*** represent p < 0.05/0.01/0.001 operated vs non-operated, ### represents p < 0.001 preoperative vs post-surgery, + represents p < 0.05 post-surgery compared to immediately after surgery (0 MPO). Graphs d–f represent percentages of totalBack to article page