Fig. 5
From: Chemokine ligand–receptor interactions critically regulate cutaneous wound healing
Chemokine expression during cutaneous wound healing. Immunohistochemical analyses of chemokine expression in healthy versus wounded human skin. Kryo sections (6 μm) of healthy and skin undergoing secondary wound healing (2, 5, 7 and 12 days after wounding) were stained with antibodies directed against CXCL9/Mig (a–d), CXCR3 (e–h), CCR2α (i), CCR2β (k), CCL1/I-309 (l), CCR8 (m), CCL27/CTACK (n), CCR10 (o), CXCL12/SDF-1α (p), and CXCR4 (q). a, e Healthy skin; b, f, i, day 2 after injury; c, g, l, q day 7 after injury; d, h, k, m–p, day 12 after injury; magnification 100 or ×250. The wound edge points to the right border of the picture. The arrow marks the beginning of the neo-epidermis. Representative results of four different donors