Table 6 The changes of oxidative stress indicators in DM sub-groups at the baseline and at end of insulin pump therapy
From: The impact of insulin pump therapy to oxidative stress in patients with diabetic nephropathy
Groups | NA | MA | CA | F value | P value |
|---|---|---|---|---|---|
3-NT (nmol/l) | |||||
Pre-treatment | 119.6 ± 11.2 | 122.0 ± 8.4 | 124.8 ± 8.9 | ||
Pro-treatment | 111.9 ± 9.2 | 114.5 ± 8.6 | 120.9 ± 9.8 | ||
D value | − 7.6 ± 5.1* | − 7.5 ± 5.0* | − 3.9 ± 4.5 | 3.316 | 0.042* |
SOD (U/ml) | |||||
Pre-treatment | 104.9 ± 19.0 | 101.7 ± 20.9 | 99.0 ± 23.7 | ||
Pro-treatment | 118.7 ± 17.8 | 114.3 ± 17.2 | 107.7 ± 20.4 | ||
D value | 13.7 ± 4.9* | 12.7 ± 6.0* | 8.6 ± 5.7 | 4.588 | 0.013* |
8-OHdG (ng/ml) | |||||
Pre-treatment | 24.5 ± 4.4 | 26.0 ± 3.9 | 26.6 ± 5.2 | ||
Pro-treatment | 20.0 ± 4.0 | 21.4 ± 4.3 | 24.3 ± 6.4 | ||
D value | − 4.5 ± 2.8* | − 4.6 ± 3.2* | − 2.3 ± 2.7 | 3.543 | 0.034* |
GSH (mg/l) | |||||
Pre-treatment | 136.3 ± 15.2 | 135.7 ± 13.4 | 126.8 ± 17.9 | ||
Pro-treatment | 147.8 ± 13.1 | 147.2 ± 9.6 | 133.8 ± 18.0 | ||
D value | 11.5 ± 6.2* | 11.5 ± 6.7* | 7.0 ± 5.2 | 3.225 | 0.045* |