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Table 2 Summary, biomechanical parameters: means and standard deviations of failure loads (N) and stiffness (N/mm) for femurs, tibiae and humeri, total and divided into subgroups of light (< 400 g) and heavy (> 400 g) animals

From: Whole bone testing in small animals: systematic characterization of the mechanical properties of different rodent bones available for rat fracture models

  Failure load (N) Failure load (N)
Light/heavy
p value failure load
Light/heavy
Failure load (N)
Δ right/left
Stiffness (N/mm) Stiffness (N/mm)
Light/heavy
p value stiffness
Light/heavy
Stiffness (N/mm)
Δ right/left
Femur (n = 40)
 Light (N = 22) 175.4 ± 45.23 138.1 ± 16.38 < 0.0001 5.6 ± 3.91 315.6 ± 63.00 280.8 ± 59.85 < 0.0001 37.4 ± 24.68
 Heavy (N = 18) 221.0 ± 18.95 16.0 ± 6.91 358.1 ± 34.64 43.1 ± 16.22
Tibia (N = 40)
 Light (N = 22) 117.1 ± 33.94 89.6 ± 13.25 < 0.0001 9.8 ± 9.48 143.8 ± 36.99 120.7 ± 32.16 < 0.0001 18.7 ± 12.76
 Heavy (N = 18) 150.6 ± 16.14 9.4 ± 10.95 171.9 ± 18.28 17.2 ± 14.72
Humerus (N = 40)
 Light (N = 22) 124.6 ± 41.13 90.23 ± 6.97 < 0.0001 5.5 ± 5.09 260.5 ± 59.97 213.6 ± 35.06 < 0.0001 14.4 ± 7.04
 Heavy (N = 18) 166.5 ± 20.79 13.2 ± 7.58 317.7 ± 20.42 19.7 ± 15.92