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Table 2 Dynamic change for serum inflammatory cytokines of NPE and CNSD children patients

From: Correlation analysis on serum inflammatory cytokine level and neurogenic pulmonary edema for children with severe hand–foot–mouth disease

Group Cases IL-6 TNF-α IL-4 IL-10 IL-17 IFN-γ
Group NPE
 1 day after admission 42 70.56 ± 17.20 58.19 ± 20.67 20.24 ± 5.13 64.11 ± 19.14 55.67 ± 42.18 56.61 ± 10.94
 3 days after admission 42 74.80 ± 20.68 52.74 ± 20.22 22.83 ± 3.63 80.14 ± 19.20 53.33 ± 25.22 58.42 ± 9.17
 5 days after admission 42 63.73 ± 23.85 30.08 ± 12.20 21.28 ± 4.50 59.92 ± 20.95 48.10 ± 27.22 55.31 ± 8.94
Group CNSD
 1 day after admission 47 65.70 ± 18.27 54.57 ± 22.01 19.05 ± 5.78 59.56 ± 22.85 48.14 ± 33.26 48.91 ± 11.73
 3 days after admission 47 55.99 ± 13.86 33.57 ± 11.43 20.38 ± 4.54 59.68 ± 16.98 44.81 ± 28.44 53.11 ± 8.96
 5 days after admission 47 49.23 ± 13.34 28.92 ± 10.09 19.60 ± 4.54 42.12 ± 16.52 34.29 ± 27.33 45.88 ± 11.06
 Value i
 Finterblock value (P value)
  7.855 (0.077) 3.644 (0.042) 4.361 (0.052) 16.823 (0.000) 3.061 (0.084) 20.142 (0.000)
 Ftime value (P value)   1.876 (0.177) 13.133 (0.001) 0.873 (0.354) 14.580 (0.001) 1.329 (0.254) 3.093 (0.045)
 Finteraction value (P value)   2.192 (0.145) 0.2919 (0.592) 0.152 (0.618) 2.612 (0.078) 3.736 (0.059) 0.513 (0.600)
  1. CNSD, central nervous system disease; NPE, neurogenic pulmonary edema; Finterblock value, It refers to the variation (F value) between NPE group and CNSD group; Ftime value, it refers to the variation of different time (1, 3, 5 days) about NPE group or CNSD group; Finteraction value, it refers to the interaction variation of group and time. ANOVA of repeated measurement data was used for the statistical test about the comparisons made between or intra-groups