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Table 2 Comparison of index among divided groups according to BMD of lumbar spine

From: Correlation of serum levels of fibroblast growth factor 23 and Klotho protein levels with bone mineral density in maintenance hemodialysis patients

Item Normal bone mass (n = 55) Osteopenia (n = 36) Osteoporosis (n = 34) P value
Age (years) 61.346 ± 16.304 66.111 ± 13.846 63.677 ± 12.557 0.317
Male [case (%)] 40 (72.73) 21 (58.33) 12 (35.29)b 0.002
Smoking [case (%)] 19 (34.55) 9 (25.00) 6 (17.65) 0.207
Diabetes [case (%)] 19 (34.55) 15 (41.67) 12 (35.29) 0.771
Hypertension [case (%)] 38 (69.09) 28 (77.78) 23 (67.65) 0.580
Hemodialysis duration [month, M (1/4, 3/4)] 61.00 (47.00, 87.50) 56.00 (46.00, 64.50) 63.00 (49.25, 90.50) 0.194
Kt/V 1.915 ± 0.492 1.708 ± 0.255 1.825 ± 0.505 0.095
BMI (kg/m2) 21.235 ± 3.358 21.330 ± 3.599 19.440 ± 2.523a,c 0.021
Hb (g/L) 106.382 ± 12.458 102.639 ± 10.944 105.559 ± 11.771 0.329
Glu [mmol/L, M (1/4, 3/4)] 6.81 (5.64, 9.07) 7.56 (5.82, 9.84) 7.26 (5.84, 9.52) 0.499
Alb (g/L) 39.762 ± 2.826 39.256 ± 2.560 39.009 ± 2.605 0.407
Adjusted Ca (mmol/L) 2.311 ± 0.236 2.287 ± 0.192 2.280 ± 0.160 0.749
P (mmol/L) 1.552 ± 0.461 1.591 ± 0.412 1.667 ± 0.511 0.522
Ca × P (mg2/dL2) 45.106 ± 13.833 44.893 ± 13.307 46.894 ± 15.541 0.804
PTH [ng/L, M (1/4, 3/4)] 328.40 (125.05, 604.10) 349.00 (182.93, 887.40) 744.00 (225.18, 1129.25) 0.062
1,25(OH)2VitD3 (ng/mL) 32.376 ± 5.923 34.585 ± 7.298 31.405 ± 6.039 0.101
FGF23 (ng/L) 93.930 ± 20.350 101.437 ± 19.277 102.865 ± 21.012 0.080
Klotho protein (ng/L) 417.108 ± 56.179 387.263 ± 53.255a 394.534 ± 56.770 0.030
  1. aP < 0.05 vs Normal bone mass
  2. bP < 0.01 vs Normal bone mass
  3. cP < 0.05 vs Osteopenia