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Table 2 Comparison of index among divided groups according to BMD of lumbar spine

From: Correlation of serum levels of fibroblast growth factor 23 and Klotho protein levels with bone mineral density in maintenance hemodialysis patients

Item

Normal bone mass (n = 55)

Osteopenia (n = 36)

Osteoporosis (n = 34)

P value

Age (years)

61.346 ± 16.304

66.111 ± 13.846

63.677 ± 12.557

0.317

Male [case (%)]

40 (72.73)

21 (58.33)

12 (35.29)b

0.002

Smoking [case (%)]

19 (34.55)

9 (25.00)

6 (17.65)

0.207

Diabetes [case (%)]

19 (34.55)

15 (41.67)

12 (35.29)

0.771

Hypertension [case (%)]

38 (69.09)

28 (77.78)

23 (67.65)

0.580

Hemodialysis duration [month, M (1/4, 3/4)]

61.00 (47.00, 87.50)

56.00 (46.00, 64.50)

63.00 (49.25, 90.50)

0.194

Kt/V

1.915 ± 0.492

1.708 ± 0.255

1.825 ± 0.505

0.095

BMI (kg/m2)

21.235 ± 3.358

21.330 ± 3.599

19.440 ± 2.523a,c

0.021

Hb (g/L)

106.382 ± 12.458

102.639 ± 10.944

105.559 ± 11.771

0.329

Glu [mmol/L, M (1/4, 3/4)]

6.81 (5.64, 9.07)

7.56 (5.82, 9.84)

7.26 (5.84, 9.52)

0.499

Alb (g/L)

39.762 ± 2.826

39.256 ± 2.560

39.009 ± 2.605

0.407

Adjusted Ca (mmol/L)

2.311 ± 0.236

2.287 ± 0.192

2.280 ± 0.160

0.749

P (mmol/L)

1.552 ± 0.461

1.591 ± 0.412

1.667 ± 0.511

0.522

Ca × P (mg2/dL2)

45.106 ± 13.833

44.893 ± 13.307

46.894 ± 15.541

0.804

PTH [ng/L, M (1/4, 3/4)]

328.40 (125.05, 604.10)

349.00 (182.93, 887.40)

744.00 (225.18, 1129.25)

0.062

1,25(OH)2VitD3 (ng/mL)

32.376 ± 5.923

34.585 ± 7.298

31.405 ± 6.039

0.101

FGF23 (ng/L)

93.930 ± 20.350

101.437 ± 19.277

102.865 ± 21.012

0.080

Klotho protein (ng/L)

417.108 ± 56.179

387.263 ± 53.255a

394.534 ± 56.770

0.030

  1. aP < 0.05 vs Normal bone mass
  2. bP < 0.01 vs Normal bone mass
  3. cP < 0.05 vs Osteopenia