Skip to main content

Table 1 Distribution of the main clinical characteristics of the subjects at the beginning of the study

From: A phase I–II controlled randomized trial using a promising novel cell-free formulation for articular cartilage regeneration as treatment of severe osteoarthritis of the knee

Clinical characteristic Arthroplasty NSAIDs BIOF2 P
Men (%) 50.0% 62.5% 50.0% 0.84*
Age (years) 62.8 ± 8.6 68.0 ± 7.1 68.5 ± 8.9 0.34**
BMI 29.5 ± 2.9 29.8 ± 2.1 28.0 ± 3.3 0.41**
Smoking 37.5% 25.0% 25.0% 0.81*
Diabetes 37.5% 25.0% 12.5% 0.51*
High blood pressure 62.5% 37.5% 50% 0.60*
WOMAC 73.3 ± 15.2 61.6 ± 16.0 62.7 ± 21.6 0.366**
Rasmussen 15.0 ± 7.0 14.0 ± 2.2 12.7 ± 3.6 0.643**
RAPID3 7.0 ± 1.5 8.3 ± 0.6 7.4 ± 1.1 0.103**
  1. Percentages or averages and standard deviation are shown. BMI body mass index.* Fisher’s exact test; **One-way ANOVA