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Table 2 Univariate and multivariate analyses for DSS for patients identified in the SEER Program database from 1973 to 2013

From: Clinical characteristics associated with primary cardiac angiosarcoma outcomes: a surveillance, epidemiology and end result analysis

Factors

Category

Univariate analysis

Multivariable analysis

HR

95% CI

P value

HR

95% CI

P value

Age

< 45/≥ 45

1.793

1.284–2.504

0.001

2.165

1.475–3.179

0.000

Race

White

  

0.936

  

0.162

Black

0.982

0.640–1.506

0.934

1.478

0.904–2.414

0.119

Other

0.913

0.558–1.494

0.717

0.807

0.469–1.389

0.439

Histological grade

Well

  

0.476

  

0.839

Moderate

1.232

0.128–11.849

0.857

0.575

0.029–11.410

0.717

Poor

2.604

0.347–19.527

0.352

1.889

0.209–17.053

0.571

Undifferentiated

2.158

0.289–16.127

0.454

1.632

0.175–15.215

0.667

Unknown

2.741

0.377–19.920

0.319

1.711

0.200–14.664

0.624

TNM stage

I

  

0.234

  

0.056

II

0.584

0.123–2.771

0.498

0.386

0.026–5.760

0.490

III

0.238

0.047–1.190

0.080

0.104

0.007–1.554

0.101

IV

0.390

0.094–1.627

0.196

0.130

0.007–2.485

0.175

Unknown

0.488

0.119–1.999

0.318

0.102

0.007–2.390

0.087

Tumour size

< 3 cm

  

0.001

  

0.026

3–5 cm

1.673

0.635–4.406

0.297

1.955

0.698–5.475

0.202

> 5 cm

2.049

0.812–5.170

0.129

3.182

1.149–8.809

0.026

Unknown

3.572

1.425–8.953

0.007

3.878

1.387–10.841

0.010

LN metastases

No

  

0.126

  

0.730

Yes

1.332

0.697–2.546

0.386

1.390

0.592–3.264

0.449

Unknown

1.430

1.010–2.024

0.044

0.946

0.337–2.651

0.916

Distant metastases

No

  

0.157

  

0.372

Yes

0.985

0.617–1.571

0.948

0.385

0.077–1.922

0.244

Unknown

1.374

0.907–2.081

0.134

1.571

0.474–5.210

0.460

Radiation

Yes/no, unknown

1.751

1.053–2.911

0.031

1.629

1.049–2.529

0.030

Surgery

Yes/no, unknown

1.442

1.034–2.011

0.031

1.427

0.946–2.153

0.090

Summary stage

Localized

  

0.172

  

0.008

Regional

0.691

0.44–1.086

0.109

0.771

0.422–1.410

0.399

Distant

0.676

0.456–1.004

0.052

1.819

0.964–3.433

0.065

Unstaged

0.656

0.161–2.678

0.557

0.294

0.063–1.363

0.118

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European Journal of Medical Research

ISSN: 2047-783X

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