Factors | Category | Univariate analysis | Multivariable analysis | ||||
---|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | ||
Age | < 45/≥ 45 | 1.793 | 1.284–2.504 | 0.001 | 2.165 | 1.475–3.179 | 0.000 |
Race | White | 0.936 | 0.162 | ||||
Black | 0.982 | 0.640–1.506 | 0.934 | 1.478 | 0.904–2.414 | 0.119 | |
Other | 0.913 | 0.558–1.494 | 0.717 | 0.807 | 0.469–1.389 | 0.439 | |
Histological grade | Well | 0.476 | 0.839 | ||||
Moderate | 1.232 | 0.128–11.849 | 0.857 | 0.575 | 0.029–11.410 | 0.717 | |
Poor | 2.604 | 0.347–19.527 | 0.352 | 1.889 | 0.209–17.053 | 0.571 | |
Undifferentiated | 2.158 | 0.289–16.127 | 0.454 | 1.632 | 0.175–15.215 | 0.667 | |
Unknown | 2.741 | 0.377–19.920 | 0.319 | 1.711 | 0.200–14.664 | 0.624 | |
TNM stage | I | 0.234 | 0.056 | ||||
II | 0.584 | 0.123–2.771 | 0.498 | 0.386 | 0.026–5.760 | 0.490 | |
III | 0.238 | 0.047–1.190 | 0.080 | 0.104 | 0.007–1.554 | 0.101 | |
IV | 0.390 | 0.094–1.627 | 0.196 | 0.130 | 0.007–2.485 | 0.175 | |
Unknown | 0.488 | 0.119–1.999 | 0.318 | 0.102 | 0.007–2.390 | 0.087 | |
Tumour size | < 3 cm | 0.001 | 0.026 | ||||
3–5 cm | 1.673 | 0.635–4.406 | 0.297 | 1.955 | 0.698–5.475 | 0.202 | |
> 5 cm | 2.049 | 0.812–5.170 | 0.129 | 3.182 | 1.149–8.809 | 0.026 | |
Unknown | 3.572 | 1.425–8.953 | 0.007 | 3.878 | 1.387–10.841 | 0.010 | |
LN metastases | No | 0.126 | 0.730 | ||||
Yes | 1.332 | 0.697–2.546 | 0.386 | 1.390 | 0.592–3.264 | 0.449 | |
Unknown | 1.430 | 1.010–2.024 | 0.044 | 0.946 | 0.337–2.651 | 0.916 | |
Distant metastases | No | 0.157 | 0.372 | ||||
Yes | 0.985 | 0.617–1.571 | 0.948 | 0.385 | 0.077–1.922 | 0.244 | |
Unknown | 1.374 | 0.907–2.081 | 0.134 | 1.571 | 0.474–5.210 | 0.460 | |
Radiation | Yes/no, unknown | 1.751 | 1.053–2.911 | 0.031 | 1.629 | 1.049–2.529 | 0.030 |
Surgery | Yes/no, unknown | 1.442 | 1.034–2.011 | 0.031 | 1.427 | 0.946–2.153 | 0.090 |
Summary stage | Localized | 0.172 | 0.008 | ||||
Regional | 0.691 | 0.44–1.086 | 0.109 | 0.771 | 0.422–1.410 | 0.399 | |
Distant | 0.676 | 0.456–1.004 | 0.052 | 1.819 | 0.964–3.433 | 0.065 | |
Unstaged | 0.656 | 0.161–2.678 | 0.557 | 0.294 | 0.063–1.363 | 0.118 |