Fig. 4

Effects of miR-145 on endothelial injury and inflammation in ACS rats. A. Serum expression of miR-145 was decreased in the ACS animal models, but was promoted by the overexpression of miR-145. b–e Serum elevated vWF (b), H-FABP (c), IL-6 (d) and TNF-α (e) in ACS rats were all abrogated by the upregulation of miR-145. *P < 0.05, **P < 0.01, ***P < 0.001, compared with the sham group; ^##P < 0.01, ^###P < 0.001, compared with the ACS model group