MicroRNA-145 is involved in endothelial cell dysfunction and acts as a promising biomarker of acute coronary syndrome

Table 1 Clinical characteristics of the participants included in this study

Characteristics	Healthy controls (n = 80)	ACS patients (n = 80)	P value
Age (years, mean ± SD)	55.41 ± 6.72	56.23 ± 6.11	0.712
Gender (female/male)	24/56	28/52	0.622
Risk factors (n)
Hypertension	46	53	0.255
Dyslipidemia	51	64	0.022
Smoking	50	48	0.801
SBP (mmHg)	118.25 ± 20.15	122.86 ± 24.31	0.714
DBP (mmHg)	81.56 ± 16.26	81.72 ± 20.88	0.985
TC (mmol/L)	4.72 ± 0.45	4.54 ± 0.68	0.155
TG (mmol/L)	1.28 ± 0.54	1.51 ± 0.44	0.276
LDL (mmol/L)	2.57 ± 0.51	2.98 ± 0.69	0.114
HDL (mmol/L)	1.47 ± 0.52	1.32 ± 0.38	0.235
CK-MB mass (ng/mL)	0.200 ± 0.22	31.72 ± 30.26	< 0.001
Myo (ng/mL)	49.57 ± 26.31	227.25 ± 142.07	< 0.001
cTnI (ng/mL)	0.022 ± 0.035	26.42 ± 22.12	< 0.001
Subtypes
AMI	–	42	–
UA	–	38	–

SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, TG triglyceride, LDL low density lipoprotein, HDL high density lipoprotein, CK-MB mass creatine kinase MB mass, Myo myoglobin, cTnI cardiac troponin I, AMI acute myocardial infarction, UA unstable angina

ISSN: 2047-783X