Fig. 2

The coronary artery structure in group N was clear, the intima was evident, the lumen size was moderate, and the thickness was uniform; however, in group S, the lumen was slightly enlarged, the wall of the tube became thinner, and the middle layer was more evident. In the group R, the coronary artery became larger and the wall became thinner and deformed. The arrow points to the coronary artery. The picture showed the results in three kinds of magnification multiple: ×100, ×200, ×400 (a). As indicated by the arrow, the brown-yellow particles can be seen in the endothelial cells and in the smooth muscle cells. And HMGB1/RAGE/NF-κB levels were highly expressed in the group S analyzed by ImageJ (×400) (b)