Table 1 Demographic and surgical characteristics at baseline
PCT elevated (n = 64) | Control (n = 232) | p value | |
|---|---|---|---|
Age (years, old) | 61.0 ± 9.9 | 60.8 ± 10.3 | 0.904 |
Male, n (%) | 41 (64.1) | 119 (51.3) | 0.070 |
Smoker, n (%) | 14 (21.9) | 52 (22.4) | 0.927 |
Coexisting conditions | |||
Hypertension, n (%) | 30 (46.9) | 117 (50.4) | 0.614 |
Diabetes mellitus, n (%) | 18 (28.1) | 65 (28) | 0.986 |
Coronary artery disease, n (%) | 52 (81.3) | 176 (75.9) | 0.364 |
NYHA grade III–IV, n (%) | 34 (53.1) | 132 (56.9) | 0.590 |
Liver disease, n (%) | 3 (4.7) | 5 (2.2) | 0.269 |
Preoperative drug therapy | |||
ACEI, n (%) | 16 (25) | 46 (19.8) | 0.368 |
Beta-blocker, n (%) | 21 (32.8) | 71 (30.6) | 0.735 |
Calcium channel blocker, n (%) | 18 (28.1) | 59 (25.4) | 0.664 |
Aspirin, n (%) | 32 (50) | 99 (42.7) | 0.296 |
Aspirin + clopidogrel, n (%) | 20 (31.3) | 56 (24.1) | 0.249 |
Preoperative troponin I (ng/mL) | 0.07 ± 0.04 | 0.08 ± 0.06 | 0.336 |
Preoperative Nt-pro-BNP (pg/mL) | 826 ± 301 | 772 ± 294 | 0.201 |
Surgery type | 0.080 | ||
CABG, n (%) | 52 (81.3) | 155 (66.8) | 0.078 |
Valve replacement, n (%) | 9 (14.1) | 61 (26.3) | 0.123 |
Other, n (%)a | 3 (4.7) | 16 (6.9) | > 0.999 |
Operation duration (min) | 305.7 ± 63.5 | 264.4 ± 51.1 | < 0.001* |
CPB time (min) | 147.2 ± 32 | 135.6 ± 22.3 | 0.008* |
Aortic clamping time (min) | 84.5 ± 17.6 | 78.4 ± 18.2 | 0.017* |
Intraoperative fluid balance (mL) | 124 ± 203 | 109 ± 229 | 0.626 |
RBC infusion (mL) | 259 ± 316 | 183 ± 215 | 0.530 |
FFP infusion (mL) | 294 ± 325 | 215 ± 228 | 0.306 |