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Table 1 Characteristics of included studies

From: Laboratory features of severe vs. non-severe COVID-19 patients in Asian populations: a systematic review and meta-analysis

Authors Publication year Country Sample size (severe/non-severe) Study designa Patients (severe/non-severe) Age group (severe vs non-severe) Quality assessment (score) References
Cai et al. 2020 China 58/240 Cross-sectional Severe/non-severe 64 ± 7.41, 40 ± 18.53 8 [12]
Cao (Min) et al. 2020 China 19/179 Single-center cohort ICU/Non-ICU 63.7 ± 16.8, 48.6 ± 15.6 7 [13]
Cao (Weiliang) et al. 2020 China 21/107 Retrospective study Severe/non-severe NR 4 [14]
Deng (a) et al. 2020 China 59/10 Cross-sectional Severe/ordinary 61.4 ± 16.7 (all patients) 4 [7]
Deng (b) et al. 2020 China 36/9 Cross-sectional ICU/ordinary cases 61.4 ± 16.7 (all patients) 4 [7]
Guan et al. 2020 China 173/926 Cohort Severe/non-severe 52 ± 18.53, 45 ± 17.05 6 [20]
Huang et al. 2020 China 13/28 Cohort ICU/Non-ICU 49 ± 14.82, 49 ± 12.23 5 [7]
Jian-ya et al. 2020 China 7/44 Retrospective, single-center case series Severe/non-severe 52 ± 11.86, 44 ± 11.86 3 [21]
Li et al. 2020 China 25/58 Retrospective study Severe or critical/ordinary group 53.7 ± 12.3, 41.9 ± 10.6 5 [25]
Liu (Jingyuan) et al. 2020 China 17/44 Prospective single-center study Severe or critical/common type 56 ± 9.75, 41 ± 18.75 5 [23]
Liu (Songqiao) (a) et al. 2020 China 53/97 Retrospective multicenter cohort study Severe or critical/asymptomatic or Mild 60.09 ± 13.86, 35.96 ± 19.88 9 [20]
Liu(Songqiao) (b) et al. 2020 China 27/470 Retrospective multicenter cohort study Severe or critical/moderate 60.09 ± 13.86, 44.47 ± 15.62 9 [20]
Liu (Yanli) et al. 2020 China 26/56 Retrospective study ARDS/Non-ARDS 61 ± 13.34, 49 ± 13.34 8 [24]
Wang et al. 2020 China 36/102 Retrospective, single-center case series (cohort) ICU/Non-ICU 66 ± 15.57, 51 ± 18.53 7 [25]
Young et al. 2020 Singapore 6/12 Descriptive case series Required supplemental O2/Did not require supplemental O2 56 ± 6.5, 37 ± 6.25 6 [27]
Zhang (Fengqin) (a) et al. 2020 China 9/23 Retrospective single center Critical/common 50.3 ± 14, 40.8 ± 12.2 6 [23]
Zhang (Fengqin) (b) et al. 2020 China 26/23 Retrospective single center Severe/common 48.9 ± 13.5, 40.8 ± 12.2 6 [23]
Zhang (Jin-jin) et al. 2020 China 58/82 Cross-sectional Severe/non-severe patients 64 ± 15.5, 51.5 ± 13 6 [22]
Zheng (a) et al. 2020 China 3/71 Cross-sectional Severe or critical)/non-severe 67.875 ± 12.22, 44.845 ± 16.79 5 [15]
Zheng (b) et al. 2020 China 3/9 Cross-sectional Severe or critical/Mild 67.875 ± 12.22, 39.444 ± 14.32 5 [15]
Zheng (c) et al. 2020 China 2/15 Cross-sectional Severe and critical/asymptomatic infected 67.875 ± 12.22, 32.667 ± 22.68 5 [15]
Zhu et al. 2020 China 43/71 Retrospective cohort study Severe group/non-severe group 76 ± 6.67, 77 ± 8.15 8 [25]
  1. a study design whether stated clearly in methods or perceived from methods