Antimicrobial peptides in human synovial membrane as (low-grade) periprosthetic joint infection biomarkers

Table 1 Preoperative blood serum inflammatory parameters: white blood cell count (WBC) and C-reactive protein (CRP)

Group	WBC(×10⁹)^a	C-reactive Protein (mg/dl)^b
Comparison of preoperative white blood cell count (WBC) and C-reactive protein in blood serum
Primary arthroplasty	6.75 ± 1.37	0.33 ± 0.22^c
Aseptic loosening	6.87 ± 1.63	0.48 ± 0.19^c
Septic loosening	7.99 ± 3.75	8.10 ± 6.26

Comparison between any two groups revealed no significant difference in WBC (a). Regarding CRP no significant difference could be found between aseptic loosening and primary arthroplasty (b). However, septic loosening led to a significant CRP increase compared to aseptic loosening (17x) and primary arthroplasty (25×) (c)
^ap > 0.05 between all groups
^bp > 0.05 between primary arthroplasty and aseptic loosening
^cp < 0.05 in comparison to PJI loosening

ISSN: 2047-783X