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Table 4 Pooled proportions of the different maternal and postnatal outcomes and coexisting disorder identified in the present systematic review

From: The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal–fetal transmission: a systematic review and meta-analysis

Pregnancy and perinatal postnatal outcome Study (n) Number of reports Pregnancies or neonate (n) Pooled % (95%–CI)
Pregnancy outcome
 PTB < 34 week 25 68 719 9.5% [7.1–39.5]
 PTB < 37 week 22 91 637 14.3% [10.2–30.2]
 > 37 week 25 330 709 46.5% [41.2–56.3]
 Pre-eclampsia 9 10 169 5.9% [3.6–11.7]
 pPROM 11 17 183 9.3% [6.6–14.8]
 FGR 14 3 108 2.8% [1.8–8.9]
 Miscarriage 4 9 62 14.5% [7.7–26.5]
 ICU admission 29 66 211 31.3% [27.2–55.5]
 Maternal death 11 15 557 2.7% [1.4–14.6]
 Cesarean delivery 32 440 772 56.9% [48.2–78.9]
 Normal delivery 17 198 692 28.6% [22.4–41.6]
Prenatal outcome
 Fetal distress 17 18 68 26.5% [17.5–39.5]
 Apgar score < 7 16 1 81 1.2% [0.0–7.7]
 Neonatal asphyxia 11 1 71 1.4% [0.0–8.9]
 Admission to NICU 8 9 73 11.3% [5.6–20.3]
 Perinatal death 21 10 452 2.2% [1.2–12.8]
 Vertical transmission 39 0 1316 0.0% [0.0–1.0]
Coexisting disorders
 Hypertension 7 81 954 8.5% [7.1–17.4]
 Gestational diabetes 9 85 881 9.6% [6.6–20.7]
 Cardiovascular disease 2 27 470 5.7% [3.0–12.1]
 Digestive disease 3 4 111 3.6% [1.1–9.8]
 Asthma 4 44 794 5.5% [2.3–36.4]
  1. PTB preterm birth, pPROM preterm premature rupture of membranes, FGR fetal growth restriction, ICU intensive care unit, NICU neonatal intensive care unit
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