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Table 1 Description of liver dysfunction between survivors and non-survivors among included studies

From: A meta-analysis of the impact of COVID-19 on liver dysfunction

Study, year

Setting

Country

Sample (dead/alive)

Age (dead/alive)

Chronic liver disease (dead/alive)

ALT (dead/alive)

AST (dead/alive)

Female gender

NOS

Yang et al. [7], 2020

ICU

China

32/20

64.6 (11.2)/51.9 (12.9)

NA

NA

NA

11/6

7

Wang et al. [13], 2020

Isolation ward

China

65/274

76 (70–83)/68 (64–74)

1/1

24 (19–49)/28 (17–43)

43 (30–68)/29 (22–43)

26/147

7

Chen N et al. [14], 2020

Isolation ward

China

113/161

68.0(62.0–77.0)/51.0(37.0–66.0)

5/6 (HBsAg +)

28.0 (18.0–47.0)/ 20.0 (14.8–32.0)

45.0 (31.0–67.0)/ 25.0 (20.0–33.3)

30/73

8

Zhou et al. [16] 2020

Isolation ward

China

54/135

69·0 (63·0–76·0)/52·0 (45·0–58·0)

NA

40.0 (24.0–51.0)/27.0 (15.0–40.0)

NA

16/56

7

Du et al. [15], 2020

Isolation ward

China

21/158

70.2(7.7)/56.0(13.5)

2/2

27.0 (20.0‒37.0)/22.0 (14.0‒40.5)

40.0 (27.0‒61.5)/27.5 (19.0‒42.0)

11/71

7

  1. Data expressed by mean (SD) or median (IQR), IQR interquartile range, ICU intensive care unit, ALT alanine aminotransferase (> 41 U/L), AST aspartate aminotransferase (> 40 U/L), HBsAg Hepatitis B virus surface antigen positivity