From: Management strategy for hematological malignancy patients with acute respiratory failure
Study | Design | Patients | Setting | Inclusion criteria | comparison | Rate of NIV failure | HRs of NIV failure | Mortality | Comments |
---|---|---|---|---|---|---|---|---|---|
Conti, 1998 | Prospective | 16 | ICU | PO2 ≤ 60 with FiO2 ≥ 0.5, RR ≥ 35 | N/A | 6.6% (1/16) | N/A | 31.3% (5/16) | NIV reduced need of IMV |
Hilbert, 2001 | RCT | 52(30 HM) | ICU | lung infiltration, fever, PO2/FiO2 < 200, RR > 30 | Oxygen/NIV | 46% | Severe acidosis, encephalopathy, hemodynamic instability, copious secretions | NIV: 38%, Oxygen: 69% | Early NIV decreased need of intubation and mortality |
Piastra, 2004 | Prospective | 4 | ICU | PO2/FiO2 < 200, RR > 30 | N/A | 0 | N/A | 50% (2/4) | NIV decreased need of IMV in pediatric HM patients |
Squadrone, 2010 | RCT | 40 | Ward | lung infiltration, SaO2 < 90% and RR > 25 | Oxygen/NIV | 0 | N/A | Oxygen: 75%, NIV: 15% | Early NIV reduced need of intubation and ICU admission |
Gristina, 2011 | Retrospective | 1302 | ICU | HM with ARF | NIV/IMV | 46% | illness severity, acute lung injury / ARDS at admission | NIV success:42%, NIV failure: 77%, IMV: 69% | Recommend NIV as first-line for HM with ARF |
Molina, 2012 | Prospective | 300 | ICU | HM patients who needed ventilation support | N/A | 60.30% | younger, non-congestive heart failure, bacteremia | NIV: 42.3%; IMV: 72.2%; NIV failure: 79.7% | NIV was preferred for ARF with reversible causes |
Belenguer, 2013 | Retrospective | 41 | ICU | HM patients who needed ventilation support | NIV/IMV | 40% | N/A | NIV: 37%; IMV: 100% | NIV decreased mortality compared with IMV |
Rathi, 2017 | Retrospective | 1614(899HM) | ICU | PO2/FiO2 < 200 | N/A | 38% | younger, high SOFA, HM, BiPAP, non-Caucasian race | NIV failure: ICU mortality:71.3%, hospital mortality: 79.5% | NIV success was associated with the best outcomes; early or late intubation had the same outcomes |
Barreto, 2020 | Prospective | 82 | ICU | PO2/FiO2 < 300, RR > 32 | Oxygen/NIV/IMV | 50.80% | high SOFA and RR, sepsis | NIV:49.2%; IMV:83.3%; Oxygen: 5.9% | NIV was feasible for HM patients though benefit was controversial |