Fig. 6

Analysis of gene connection and expression of DCGs in discovery cohort. The analysis of clustering coefficient and gene expression revealed CCL20 and NR4A3 as hub genes (A). The CCL20 is a chemoattractant while NR4A3 is a nuclear factor receptor (B). Subgraphs of CCL20 and NR4A3 substantiate their important roles in AMI development (C). Networks are presented under threshold 0.5 and 0.7. Darker lines represent connections under threshold 0.7; lighter lines represent connections under threshold 0.5. DCGs differential connectivity genes; CC clustering coefficient; GeExp gene expression