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Table 1 Baseline characteristics after adjusting for baseline covariates

From: Clinical characteristics and outcomes of critically ill mechanically ventilated COVID-19 patients receiving interleukin-6 receptor antagonists and corticosteroid therapy: a preliminary report from a multinational registry

Variables

Steroids

IL6-RAs

Both

P

SMD

Na

811.6

596.8

698.9

  

Male

528 (65.1)

430 (72.1)

433 (62)

0.25

0.145

Age [mean (SD)]

60.9 (14.2)

60.6 (13.8)

61.5 (12.8)

0.90

0.042

Weight at admission [mean (SD)]

91.3 (27.9)

92.7 (26.3)

94.5 (29.9)

0.62

0.076

Ethnic group

0.93

0.113

 Hispanic

163 (20.1)

128 (21.5)

147 (21.3)

  

 Non-hispanic

385 (47.4)

285 (47.8)

325 (47)

  

CVD

176 (21.6)

75 (12.6)

161 (23)

0.11

0.183

Asthma/COPD

143 (17.6)

84 (14.1)

147 (21)

0.33

0.121

Hydroxychloroquine

164 (20.2)

181 (30.2)

180 (26)

0.15

0.141

Azithromycin

300 (37)

279 (46.7)

294 (42.1)

0.32

0.122

Antiviral

145 (18)

78 (13.1)

141 (20.2)

0.42

0.136

ARDS grade

0.79

0.148

 Mild (P:F 200–300)

22 (2.8)

17 (3)

23 (3.3)

  

 Moderate (P:F 100–199)

83 (10.7)

38 (6.5)

41 (6)

  

 Severe (P:F < 100)

132 (16.9)

79 (13.8)

113 (16.2)

  

Any anticoagulant

693 (85.3)

504 (84.4)

560 (80.1)

0.46

0.093

Therapeutic anticoagulation

179 (22.1)

87 (14.6)

162 (23.1)

0.15

0.147

FiO2 lowest [mean (SD)]

0.56 (0.25)

0.52 (0.24)

0.57 (0.24)

0.43

0.127

Neuromuscular blocker

659 (82)

520 (87)

625 (89.4)

0.15

0.16

Vasopressors

638 (78.6)

506 (84.8)

612 (87.5)

0.14

0.16

  1. Data presented as n (%) unless otherwise specified
  2. ARDS acute respiratory distress syndrome, CVD cardiovascular diseases, COPD chronic obstructive pulmonary disease, IL6-RAs interleukin-6 receptor antagonists, SMD standardized mean difference, SD standard deviation, P:F ratio of arterial oxygen partial pressure (PaO2 in mmHg) to fractional inspired oxygen
  3. aThe total number is slightly different in the post-IPW pseudo-data set as a result of the weighting. Each individual gets own weight that is used for further analysis. Multiplication by these weights can usually results in decimals