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Table 1 Baseline characteristics after adjusting for baseline covariates

From: Clinical characteristics and outcomes of critically ill mechanically ventilated COVID-19 patients receiving interleukin-6 receptor antagonists and corticosteroid therapy: a preliminary report from a multinational registry

Variables Steroids IL6-RAs Both P SMD
Na 811.6 596.8 698.9   
Male 528 (65.1) 430 (72.1) 433 (62) 0.25 0.145
Age [mean (SD)] 60.9 (14.2) 60.6 (13.8) 61.5 (12.8) 0.90 0.042
Weight at admission [mean (SD)] 91.3 (27.9) 92.7 (26.3) 94.5 (29.9) 0.62 0.076
Ethnic group 0.93 0.113
 Hispanic 163 (20.1) 128 (21.5) 147 (21.3)   
 Non-hispanic 385 (47.4) 285 (47.8) 325 (47)   
CVD 176 (21.6) 75 (12.6) 161 (23) 0.11 0.183
Asthma/COPD 143 (17.6) 84 (14.1) 147 (21) 0.33 0.121
Hydroxychloroquine 164 (20.2) 181 (30.2) 180 (26) 0.15 0.141
Azithromycin 300 (37) 279 (46.7) 294 (42.1) 0.32 0.122
Antiviral 145 (18) 78 (13.1) 141 (20.2) 0.42 0.136
ARDS grade 0.79 0.148
 Mild (P:F 200–300) 22 (2.8) 17 (3) 23 (3.3)   
 Moderate (P:F 100–199) 83 (10.7) 38 (6.5) 41 (6)   
 Severe (P:F < 100) 132 (16.9) 79 (13.8) 113 (16.2)   
Any anticoagulant 693 (85.3) 504 (84.4) 560 (80.1) 0.46 0.093
Therapeutic anticoagulation 179 (22.1) 87 (14.6) 162 (23.1) 0.15 0.147
FiO2 lowest [mean (SD)] 0.56 (0.25) 0.52 (0.24) 0.57 (0.24) 0.43 0.127
Neuromuscular blocker 659 (82) 520 (87) 625 (89.4) 0.15 0.16
Vasopressors 638 (78.6) 506 (84.8) 612 (87.5) 0.14 0.16
  1. Data presented as n (%) unless otherwise specified
  2. ARDS acute respiratory distress syndrome, CVD cardiovascular diseases, COPD chronic obstructive pulmonary disease, IL6-RAs interleukin-6 receptor antagonists, SMD standardized mean difference, SD standard deviation, P:F ratio of arterial oxygen partial pressure (PaO2 in mmHg) to fractional inspired oxygen
  3. aThe total number is slightly different in the post-IPW pseudo-data set as a result of the weighting. Each individual gets own weight that is used for further analysis. Multiplication by these weights can usually results in decimals