Table 5 Documented complication during hospitalization after adjusting for baseline covariates
Variables | Steroids | IL6-RAs | Both | p |
|---|---|---|---|---|
Na | 804.1 | 582.4 | 689.6 | Â |
None | 35 (4.3) | 40 (6.8) | 16 (2.3) | 0.30 |
Acute cardiac injury | 63 (7.9) | 56 (9.6) | 33 (4.8) | 0.32 |
Acute kidney injury | 292 (36.4) | 280 (48.1) | 277 (40.2) | 0.15 |
Cardiac arrest | 155 (19.3) | 84 (14.4) | 114 (16.5) | 0.52 |
Cardiac arrhythmia new onset | 101 (12.6) | 67 (11.4) | 66 (9.6) | 0.72 |
Coagulation disorder disseminated intravascular coagulation | 34 (4.3) | 59 (10.0) | 50 (7.3) | 0.23 |
Deep vein thrombosis | 51 (6.3) | 59 (10.1) | 68 ( 9.9) | 0.34 |
Empyema | 3 (0.3) | 5 (0.9) | 5 (0.7) | 0.70 |
High troponin level | 97 (12.1) | 57 (9.8) | 134 (19.4) | 0.04 |
Liver dysfunction/acute liver failure | 118 (14.6) | 139 (23.9) | 82 (11.9) | 0.04 |
Lung abscesses | 3 (0.3) | 0 (0) | 5 (0.7) | 0.45 |
Myocarditis | 8 (1.0) | 7 (1.3) | 0 (0) | 0.28 |
Pneumothorax | 54 (6.8) | 35 (6.0) | 30 (4.4) | 0.64 |
Causative microbiology and rate of secondary infections | ||||
 Respiratory viral panel (RVP) PCR positiveb | 1 (0.2) | 2 (1.2) | 0 (0) | 0.72 |
 Bacterial pneumonia | 192 (23.9) | 173 (29.7) | 197 (28.5) | 0.46 |
 Cytomegalovirus PCR positive | 2 (0.3) | 0 (0) | 1 (0.9) | 0.40 |
 Legionella urine Ag positive | 0 (0) | 1 (0.6) | 0 (0) | 0.32 |
 Blood cultures positivec | 93 (21.9) | 27 (17.2) | 17 (19.3) | 0.44 |
 Hospital day(s) positive blood cultures performed, median [IQR] | 7 [0.25; 14] | 14 [1; 22] | 10 [0.75; 13] | 0.14 |
 Sputum culture positived | 167 (50.6) | 65 (53.3) | 34 (45.9) | 0.61 |
 Hospital day(s) positive sputum culture performed, median [IQR] | 4 [1; 11] | 5 [1.5; 9] | 5 [1; 13.5] | 0.87 |
 Urine culture positivee | 74 (29.2) | 23 (20.2) | 11 (19.6) | 0.10 |