Observational case series: six neurosurgical patients with septic shock demonstrating clinical improvement after a combination of standard care and blood purification

Table 1 Patient characteristics, major medical history, antibiotic therapy, scoring pre- and post-treatment

Case no.	Name	Sex	Age	Major pathology	Source of infection	Pathogen	Antibiotics	Time before CBP hours	Initial SOFA score	Initial GCS	Initial FOUR
1	S	F	71	Brain tumor removal	Urinary tract infection	Not determined	Meropenem, linezolid, ciprofloxacin	10	12	10	11
2	G	F	82	Aneurysm clipping after SAH	Pneumonia	Klebsiella pneumoniae	Meropenem, linezolid, fluconazole, polymyxin E	20	12	6	8
3	Ch	M	55	Brain trauma	Bloodstream infection	Staphylococcus epidermidis	Meropenem, tigecycline, polymyxin E	10	11	6	8
4	P	M	29	Aneurysm clipping after SAH	Bloodstream infection	Escherichia coli	Meropenem, linezolid, fluconazole, polymyxin E	6	16	4	5
5	K	M	56	Aneurysm clipping after SAH	Bloodstream infection	Escherichia coli, Morganella morganii	Meropenem, linezolid, polymyxin E	20	16	4	2
6	M	M	68	Brain tumor removal, PE, post-CPR	Pneumonia	MSSA	Meropenem, linezolid	6	18	10	13

ISSN: 2047-783X