Skip to main content

Table 5 ECMO use and outcomes

From: Extracorporeal membrane oxygenation support for SARS-CoV-2: a multi-centered, prospective, observational study in critically ill 92 patients in Saudi Arabia

Variable

ECMO

group (n = 92)

Duration of ECMO use, days

15.4 ± 10.1 (1–52)

Indication for ECMO insertion

 COVID-19-related ARDS

88 (95.6%)

 Other

4 (4.3%)

Cannulation procedure

 Percutaneous

85 (92.4%)

 Cutdown

2 (2.2%)

ECMO insertion location

 Same center the patient is in now

45 (48.9%)

 Another hospital then transported to this center

45 (48.9%)

Type of transportation

 Ground transport

38 (41.3%)

 Air medical transport

7 (7.6%)

 Distance from the referring facility to the receiving hospital, kilometers

155.9 ± 279.2 (2–1,045)

 Duration of transportation, minutes

4.7 ± 6.5 (0.6–34.8)

Initial ECMO mode

 VV ECMO

86 (93.5%)

 VA ECMO

3 (3.3%)

 VAV ECMO

1 (1.1%)

 Prone positioning within 24 h of ECMO initiation

39 (42.4%)

Mode of ventilation 2 h pre-ECMO

 PC

14 (0.9%)

 VC

23 (1.5%)

 PRVC

17 (1.1%)

 SIMV

1 (0.1%)

 HFOV

1 (0.1%)

 Other

3 (0.2%)

Mode of ventilation 72 h post-ECMO

 PC

51 (55.4%)

 VC

25 (27.2%)

 PRVC

8 (8.7%)

 HFOV

1 (1.1%)

 CMV

1 (1.1%)

 Prone positioning after 72 h of ECMO initiation

5 (5.4%)

 ECMO maximum (highest) blood flow, L/minute

4.5 ± 0.8 (2–8)

 ECMO maximum (highest) sweep gas flow, L/minute

6 ± 1.8 (3–10)

Blood transfusion products used while patient was on ECMO

 Packed red blood cells

75 (81.5%)

 Fresh frozen plasma

40 (43.5%)

 Platelets

33 (35.8%)

 Cryoprecipitate

14 (15.2%)

 Factor VII

2 (2.2%)

 Tranexamic acid

4 (4.3%)

ECMO mode conversion data

 Patient underwent conversion (change) of ECMO mode

4 (4.3%)

 Mode of ECMO was changed (from-to)

 

 VV to VAV

1 (1.1)

 VV to VA

2 (2.2%)

 VAV to VV

1 (1.1%)

Complications during ECMO

 Bleeding from cannulation site

30 (32.6%)

 Oxygenator failure requiring circuit change

8 (8.7%)

 ECMO circuit clotting

7 (7.6%)

ECMO outcome

 Successful decannulation

42 (45.6%)

 Withdrawal of ECMO support

5 (5.4%)

 Death

45 (48.9%)

 Cause of death

 

 Septic shock

18 (19.6%)

 Multiple organ failure

10 (10.9%)

 Cardiac arrest

4 (4.3%)

 Do-not-resuscitate order

4 (4.3%)

 Tension pneumothorax

1 (1.1%)

 Severe lung fibrosis

1 (1.1%)

 Intra-abdominal abscess

1 (1.1%)

 Intracerebral hemorrhage

2 (2.2%)

 Severe hypotension

2 (2.2%)

 Cardiogenic shock

1 (1.1%)

 Mixed shock

1 (1.1%)

  1. Data are presented as mean ± SD (minimum–maximum), or number (%), unless otherwise indicated
  2. APRV airway pressure release ventilation, ARDS acute respiratory distress syndrome, CMV continuous mandatory ventilation, COVID-19 coronavirus disease 2019, ECMO extracorporeal membrane oxygenation, HFOV high frequency oscillatory ventilation, PC pressure control, PRVC pressure-regulated volume control, PS pressure support, SD standard deviation, SIMV synchronized intermittent mandatory ventilation, VA venoarterial, VAV veno–arterial–venous, VC volume control, VV venovenous
  3. Percentages do not total 100% owing to missing data