Table 8 Laboratory data
Laboratory data of patients during ICU stay | Day 1 | Day 4 | Day 7 | Day 11 | Day 15 | Day 21 | Day 28 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Non-ECMO | ECMO | Non-ECMO | ECMO | Non-ECMO | ECMO | Non-ECMO | ECMO | Non-ECMO | ECMO | Non-ECMO | ECMO | Non-ECMO | ECMO | |
Hemoglobin level, g/dl | 12.3 (6.2) | 12.2 (14.9) | 12.8 (4.4) | 12.6 (5.9) | 21 (31) | 14.1 (19.2) | 18.9 (27.5) | 12.6 (18.1) | 20 (29.4) | 14.6 (23.7) | 21.2 (30.9) | 14.8 (20.6) | 22.4 (33.6) | 11.3 (12.5) |
White blood cell count, × 109/L | 11.9 (34.3) | 14 (9.3) | 11 (8.2) | 15.1 (7.7) | 13.6 (35.5) | 17.4 (8.9) | 14.6 (9.4) | 17 (8.9) | 13.3 (8.6) | 15.9 (10.4) | 12.1 (9) | 14.3 (8.4) | 12 (6.7) | 11.4 (7) |
Absolute lymphocyte count, × 109/L | 2.4 (16.3) | 2 (4.6) | 12.4 (324.5) | 1.6 (2.7) | 1.8 (6) | 2.3 (4.7) | 3.1 (28.3) | 1.9 (3.1) | 2.5 (9.4) | 1.5 (1.8) | 1.9 (7) | 1.8 (1.9) | 7.1 (51.8) | 1.5 (2.6) |
Absolute neutrophil count, × 109/L | 13.3 (55.8) | 18.9 (22.1) | 12.2 (36.4) | 13.1 (11) | 11.1 (12) | 17.8 (14.3) | 14.3 (20.7) | 16.6 (13.6) | 16.1 (60) | 13.6 (13) | 9.7 (9.2) | 25.3 (30.7) | 10.6 (12.6) | 12.3 (14.7) |
Platelets, × 109/L | 253.5 (115) | 205.7 (100.7) | 288.6 (131.6) | 194 (106.6) | 309.4 (176.6) | 189 (101.2) | 280.4 (146.7) | 152.8 (89.4) | 250.8 (139) | 146 (116.6) | 218.5 (148.4) | 136.4 (90.2) | 232.9 (132) | 186.9 (150.9) |
Activated partial thromboplastin time, seconds | 41 (25.9) | 54.9 (42.9) | 44.1 (51.5) | 52.3 (25.8) | 43.1 (24.7) | 57.6 (33.5) | 49.2 (81.3) | 60.7 (37.2) | 44.7 (25) | 56.9 (34.5) | 48 (26.7) | 47.9 (25.4) | 45.3 (24.2) | 46.3 (25) |
Prothrombin time, seconds | 16.6 (38.3) | 13.8 (2.7) | 16.2 (15.2) | 13.5 (2.7) | 15.2 (7.1) | 16.9 (18.2) | 15.2 (8.2) | 19 (24.5) | 15.3 (4.4) | 14.5 (4.4) | 15.3 (4.8) | 15 (7.3) | 15.4 (4.5) | 16.3 (7.7) |
Fibrinogen, mg/dl | 161.2 (324.7) | 4.9 (4.3) | 171.6 (456.5) | 12.8 (48.4) | 137 (303.1) | 8.8 (30.2) | 177.5 (300.2) | 17 (47.4) | 163.3 (270.6) | 18.5 (51.1) | 134.8 (235.7) | 14 (32.5) | 148 (253.8) | 21.5 (51.3) |
Aspartate transaminase, U/l | 176.2 (1462.9) | 157.6 (510.1) | 114.5 (228.6) | 233.2 (998.7) | 94.5 (348.6) | 249.1 (1,095.8) | 94.6 (259.3) | 190.8 (704) | 82.2 (146.5) | 126 (331.2) | 98.3 (255.6) | 86.3 (156.3) | 48.5 (44.5) | 253.2 (850.2) |
Alanine transaminase, U/l | 105.1 (438.4) | 86.4 (148.1) | 108.7 (198.4) | 167.4 (221.2) | 92.7 (228.4) | 148.4 (361.2) | 78 (90.6) | 112 (171.9) | 94.1 (322) | 142.7 (277.7) | 64.9 (111.7) | 121.6 (245.9) | 59.1 (87.6) | 65.3 (72.4) |
Bilirubin, mg/dl | 17.5 (69) | 25.1 (51.9) | 19.4 (30) | 48.9 (270) | 17.4 (39.9) | 59.4 (300) | 18.1 (31) | 25.7 (26) | 21.4 (56) | 39.3 (49.1) | 24.2 (75.4) | 38 (59.1) | 14.1 (16.4) | 54.5 (91.6) |
Erythrocyte sedimentation rate, mm/hour | 79.3 (414.7) | 63.5 (68.2) | 63.6 (39.5) | 65.5 (46) | 91.5 (204.9) | 44.8 (40.3) | 70.7 (41.4) | 41.6 (41) | 61.8 (41.7) | 47.2 (45.2) | 105.5 (154.6) | 37.5 (44.1) | 45 (41.3) | 31.1 (42.2) |
Creatinine, mg/dl | 146.3 (374.8) | 147.6 (176.8) | 155.4 (276) | 157.6 (179.1) | 151.8 (167) | 136.9 (121.7) | 162.7 (172.8) | 136.9 (142.4) | 158.9 (157) | 137.3 (127.7) | 175.7 (278.8) | 124 (103.3) | 155.3 (144.4) | 109.4 (118.5) |
Lactate, mmol/l | 11 (54.8) | 51.4 (188.7) | 7.1 (44.8) | 2.1 (3.1) | 14.1 (87.9) | 43.4 (179.7) | 10.5 (70.5) | 24.7 (111.1) | 19.6 (134.4) | 33.3 (131.7) | 2.3 (3.1) | 63.7 (160) | 1.6 (1) | 32.5 (77.3) |
Procalcitonin, ng/ml | 20.4 (171.4) | 24.4 (80.5) | 15.3 (98.4) | 19.8 (39) | 6.8 (48.1) | 5.3 (13.5) | 21.3 (197.4) | 6.7 (12.4) | 10.7 (63.6) | 14.6 (37) | 24 (101.8) | 1.7 (1.9) | 28.7 (177.6) | 2.8 (0.5) |
Lactate dehydrogenase, U/l | 637.3 (827) | 752.3 (675.6) | 749.2 (3797.2) | 1,094.2 (2570.4) | 611 (564.2) | 1,097.5 (2714.7) | 578.5 (416.3) | 697 (359.8) | 580.5 (631) | 694.9 (511.7) | 508.8 (494.7) | 791.8 (907) | 448.5 (256.1) | 498.1 (333.3) |
C-reactive protein, mg/L | 160.8 (327.6) | 60.6 (77) | 92.2 (107.8) | 35.7 (48) | 73.5 (109.6) | 47.1 (70.7) | 74.1 (231.4) | 126.6 (301) | 68.5 (91.8) | 182.8 (341.1) | 83.1 (99) | 81.8 (90.9) | 74.5 (65.4) | 318.7 (523.4) |
Troponin I, ng/ml | 8.5 (53) | 219.7 (1285.7) | 31.7 (370.9) | 12 (44) | 31.9 (296.4) | 3.9 (9.9) | 5.2 (22.2) | 1.6 (5) | 8.7 (25.2) | 13.7 (38.4) | 12 (50.3) | 50.3 (128.8) | 1.8 (2.4) | 0.6 (1.1) |
Troponin T, ng/ml | 8.9 (35) | 13.5 (20.6) | 21.7 (75.2) | 11.4 (22.4) | 25 (87.4) | 24.5 (32.3) | 24.4 (55.3) | 57.7 (99.6) | 38.2 (83.5) | 212.5 (320.9) | 81.4 (144.7) | 491.5 (794.2) | 122.1 (278.4) | 488.5 (684.2) |
hs-cTnT, ng/l | 34 (46.1) | 117.9 (219.5) | 0.01 (0) | 117.5 (219.7) | 12 (16.9) | 166.4 (284.6) | 0.01 (0) | 0.6 | 13 (20.1) | 4 (5.4) | 9 (14.8) | 15.7 | 7.9 (6.6) | 60 (103) |
Creatine kinase, U/l | 643.5 (3404.3) | 687.1 (1597.4) | 640.4 (2285) | 581 (1160) | 560.8 (2107.5) | 1,361.7 (5797.3) | 447.6 (926) | 408.4 (604) | 739.8 (3191.7) | 520 (872.5) | 614.7 (1661) | 331.9 (500.3) | 209.8 (258) | 295.9 (367.4) |
D-dimer, mg/l | 30.3 (230.8) | 7 (9.8) | 6.2 (35) | 6.3 (7.4) | 21.3 (344.7) | 269.7 (1192.7) | 32.2 (472) | 166.1 (533.7) | 72.5 (726.3) | 927.6 (3427.8) | 4 (5.3) | 13.8 (19.8) | 17 (109.4) | 410.5 (1229.5) |
Ferritin, µg/L | 1704 (4579.4) | 1581.5 (2629) | 2706.1 (22,776) | 1313.8 (2021.7) | 2535.4 (23,851) | 2671.6 (11,540.2) | 1972.5 (10,956) | 991.8 (1279.7) | 1533.1 (3620.3) | 797.4 (1029.2) | 1240.9 (1801.3) | 1591.2 (2700) | 1504.1 (4228.4) | 1987.6 (2371) |
NT-proBNP, (pg/ml) | 2943.8 (9193.3) | 2312.3 (2648) | 1923.5 (7945) | 6250 (13.990) | 2377 (6050) | 4526 (6318.7) | 1661.2 (2752) | 4710.5 (6303.8) | 3078 (5932) | 544.5 (365.6) | 2481.6 (2914.9) | 639 (3201) | 2529 (2138.5) | 2001.6 (2109) |
BNP, (pg/ml) | 3407.6 (12,607.7) | 446 (705.3) | 387.9 (535.1) | 1,485 (3,361.7) | 230.7 (147.2) | 1398.1 (2804.2) | 1406.9 (1899.4) | 765.3 (998) | 20 (29.4) | 390.6 (534.6) | 172.2 | 1710 (987) | 22.4 (33.6) | 193 (36) |