Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects

Table 3 Summary of previous published studies

Publication	Patients	Dose (Gy)	Technique	Response-rate (%)	CR (%)	PR (%)	NR (%)
Publication	n	ED/GD	Technique	Response-rate (%)	CR (%)	PR (%)	NR (%)
Richarz (1924) [57]	5	–	Orthovolt	100	80	20	0
Pannewitz (1933) [58]	88		Orthovolt
Mustakallio & Laitinien (1939) [59]	17	1.0–1.5/4.0–6.0	Orthovolt	82	76	6	18
Cocchi (1943) [60]	6	1.8/9.0	Orthovolt	83	33	50	17
Pizon (1957) [61]	3	–	Orthovolt	100	100	0	0
Wieland & Kuttig (1965) [62]	16	1.0/4.0	Cobalt-60	100	74	13	13
Mitrov & Harbov (1967) [63]	1520	0.5–1.5/3.0–9.0	Orthovolt	88	50	38	12
Zschache (1972) [64]	49	0.74–1.5/2.25–4.5	Orthovolt	86	12	74	14
Mantell (1978) [65]	26	2.0/10.0	240–300 kV	65	53	12	35
Basche et al. (1980) [66]	102	0.3–0.5/4.0	120 kV	90	32	58	10
Sautter-Bihl et al. (1993) [67]	15	0.5–1.0/2.5–6.0	Cobalt-60	80	60	20	20
Schäfer et al. (1995) [68]	11	0.5–1.0/2.0–4.0	Cobalt-60	72	13	59	27
Seegenschmiedt et al. (1996) [69]	72	1.0/12.0	250 kV	100	67	33	0
Seegenschmiedt et al. (1996) [69]	98	0.3–0.5/3.0–5.0	200 kV	95	72	23	5
Lederer et al. (1998) [70]	21	1.0/6.0	4–6 MV, cobalt-60	91	43	48	9
Oehler & Hentschel (2000) [71]	258	–	Orthovolt	88	81	7	12
Koeppen et al. (2000) [72]	673	0.3/1.5–3.0	250 kV	78	13	65	22
Schreiber et al. (2000) [73]	87	1.0/6.0	6MV	86	67	19	14
Heyd et al. (2001) [74]	105		6MV	88	46	42	12
Glatzel et al. (2001) [75]	161	1.0/6.0–12.0	175 kV	89	63	26	11
Mücke et al. (2003) [76]	117	0.5/5.0–1.0	6MV	89	73	16	11
Schneider et al. (2004) [77]	68	0.25–1.0/5.0	10MV	90	53	37	10
Heyd et al. (2006) [78]	252	1.0/6.0	6MV	85.6	44.3	19.7	15.4
Heyd et al. (2007) [79]	130	0.5–1.0/3.0–6.0	6MV	87.7			12.3
Niewald et al. (2012) [80]	66	1.0–0.1/6.0–0.6	6MV

CR complete remission, ED single dose, GD total dose, NR no remission, PR partial remission

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